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甲状腺功能亢进症伴发焦虑障碍的相关因素探讨 被引量:8

Research about the related factors of anxiety disorder in patients with hyperthyroidism
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摘要 目的初步探讨甲状腺机能亢进症(甲亢)患者伴发焦虑的相关影响因素。方法于我院门诊选取甲亢初诊患者90例,通过焦虑量表(SAS)筛查分为单纯甲亢组(45例)和甲亢伴焦虑组(45例)。应用化学发光免疫分析仪测定FT3、FT4、TSH、TPO-Ab、TG-Ab,对伴发焦虑患者应用心理他评量表(HAMA)进行评估,抗甲状腺药物治疗8周后再次测评以观察变化。结果甲亢伴焦虑组FT3、FT4水平较单纯甲亢组显著升高(P<0.05),且年龄、FT3与SAS标准分呈正相关关系,抗甲状腺药物治疗8周后,HAMA评分较前下降(P<0.05)。结论甲亢伴焦虑患者甲状腺激素水平较单纯甲亢患者升高更明显,FT3、年龄与甲亢伴发焦虑的发病有关,抗甲状腺药物治疗对改善焦虑症状有效。 Objective To investigate the relative factors contributing to anxiety disorder in the patients with hyperthyroidism initially. Methods 90 hyperthyroid patients were chosen in outpatient service from our hospital. The patients were screened into two groups by SAS scale-hyperthyroidism with anxiety and pure hyperthyroidism. Determined the concentration of FT3,FT4,TSH,TPO-Ab,TG-Ab for all patients.Evaluated the degree of anxiety disorder by HAMA scale. After the treatment of 8 weeks'anti-thyroid medication,reviewed and assessed it again. Results The rise of FT3,FT4 in hyperthyroidism patients with anxiety was significantly higher than the pure group(P 〈 0.05).The age and FT3 were positively correlated to the SAS standard score. After the treatment of anti-thyroid medication,the HAMA score was decreased(P 〈 0.05). Conclusion The increase of FT3 is higher in the patients of hyperthyroidism with anxiety than that in the pure hyperthyroidism.The age and the level of FT3 are positively correlated to the anxiety disorders in hyperthyroidism. The anxiety symptoms can be improved after the anti-thyroid treatment.
机构地区 潍坊医学院
出处 《中国医药科学》 2013年第10期213-214,共2页 China Medicine And Pharmacy
关键词 甲亢 焦虑 相关因素 Hyperthyroidism Anxiety Correlative factor
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