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从Alchieve研究看预混胰岛素类似物治疗糖尿病的优势 被引量：2

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摘要 血糖控制是糖尿病治疗的关键。英国糖尿病前瞻性研究（UKPDS）结果显示，糖化血红蛋白（HbAlc）每下降1％，糖尿病微血管并发症引起的截肢和死亡风险下降43％，大血管并发症风险下降37％，心力衰竭风险下降16％。
作者 杨文英
机构地区 中日友好医院内分泌科
出处 《中华糖尿病杂志》 CAS CSCD 2013年第5期316-318,共3页 CHINESE JOURNAL OF DIABETES MELLITUS
关键词 英国糖尿病前瞻性研究 预混胰岛素类似物 治疗 糖尿病微血管并发症 糖化血红蛋白 死亡风险 大血管并发症 血糖控制
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献22

  • 1Stratton IM,Adler Al,Neil HA,et al. Association of glycaemiawith raacrovascular and microvascular complications of type 2diabetes ( UKPDS 35 ) : prospective observational study. BMJ,2000,321:405412.
  • 2Wright A,Burden AC,Paisey RB, et al. Sulfonylureainadequacy : efficacy of addition of insulin over 6 years in patientswith type 2 diabetes in the U. K. Prospective Diabetes Study(UKPDS 57). Diabetes Care,2002,25:330-336.
  • 3Garber AJ,Ligthelm R,Christiansen JS,et al. Premixed insulintreatment for type 2 diabetes: analogue or human?. Diabetes ObesMetab ,2007,9:630-639.
  • 4Home PD, Hallgren P, Usadel KH, et al. Pre-meal insulin aspartcompared with pre-meal soluble human insulin in type 1 diabetes.Diabetes Res Clin Pract, 2006,71:131-139.
  • 5Qayyum R, Bolen S, Maruthur N, et al. Systematic review:comparative effectiveness and safety of premixed insulin analoguesin type 2 diabetes. Ann Intern Med,2008 ,149 : 549-559.
  • 6Philis-Tsimikas A, Charpentier G,Clauson P, et al. Comparisonof once-daily insulin detemir with NPH insulin added to a regimenof oral antidiabetic drugs in poorly controlled type 2 diabetes. ClinTher,2006,28:1569-1581.
  • 7Shah SN, Litwak L,Haddad J,et al. The Alchieve study: a60 000-person,global, prospective,observational study of basal,meal-time, and biphasic insulin analogs in daily clinical practice.Diabetes Res Clin Pract,2010,88 Suppl 1 ;S11-16.
  • 8Home P,Naggar NE,Khamseh M,et al. An observational non-interventioned study of people with diabetes beginning or changedto insulin analogue therapy in non-Westem countries : theAlchieve study. Diabetes Res Clin Pract,2011,94:352-363.
  • 9杨文英,李玉秀,陈莉明,石勇铨,彭永德,雷闽湘.双时相门冬胰岛素30在中国人群中的临床应用——A1chieve观察性研究结果[J].中华糖尿病杂志,2012,4(10):607-612. 被引量：27
  • 10Soewondo P, Hussein Z, Shah S, et al. Delay in beginning oroptimizing insulin therapy despite poor glycemic control: data fromthe Alchieve study. Diabetes,2011 ,60 Suppl 1 :A287.

二级参考文献11

  • 1Danne T,Aman J,Schober E. A comparison of postprandial and preprandial administration of insudin aspart in children and adolescents with type 1 diabetes[J].Diabetes Care,2003.2359-2364.
  • 2Hermansen K,Davies M,Derezinski T. A 26-week,randomized,parallel,treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucoselowering drugs in insulin-na?ve people with type 2 diabetes[J].Diabetes Care,2006.1269-1274.
  • 3Holman RR,Farmer AJ,Davies MJ. Three-year efficacy of complex insulin regimens in type 2 diabetes[J].New England Journal of Medicine,2009.1736-1747.
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  • 5Garber AJ,Wahlen J,Wahl T. Attainment of glycaemic goals in type 2 diabetes with once-,twice-,or thrice-daily dosing with biphasic insulin aspart 70/30 (The 1-2-3 study)[J].Diabetes,Obesity and Metabolism,2006.58-66.
  • 6Home P,Naggar NE,Khamseh M. An observational noninterventional study of people with diabetes beginning or changed to insulin analogue therapy in non-Western countries:the Alchieve study[J].Diabetes Research and Clinical Practice,2011.352-363.
  • 7Valensi P,Benroubi M,Borzi V. Initiating insulin therapy with,or switching existing insulin therapy to,biphasic insulin aspart 30/70 (NovoMix 30) in routine care:safety and effectiveness in patients with type 2 diabetes in the IMPROVE observational study[J].International Journal of Clinical Practice,2009.522-531.
  • 8Wenying Y,Benroubi M,Borzi V. Improved glycaemic control with BIAsp 30 in insulin-na(i)ve type 2 diabetes patients inadequately controlled on oral antidiabetics:subgroup analysis from the IMPROVE study[J].Current Medical Research and Opinion,2009.2643-2654.
  • 9Boehm BO,Vaz JA,Brφndsted L. Long-term efficacy and safety of biphasic insulin aspart in patients with type 2 diabetes[J].European Journal of Internal Medicine,2004.496-502.
  • 10McNally PG,Dean JD,Morris AD. Using continuous glucose monitoring to measure the frcquency of low glucose values when using biphasic insulin aspart 30 compared with biphasic human insulin 30:a double-blind crossover study in individuals with type 2 diabetes[J].Diabetes Care,2007.1044-1048.

共引文献26

同被引文献11

二级引证文献19

中华糖尿病杂志
2013年 第5期

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