期刊文献+

甲状腺眼病的免疫治疗 被引量:3

Immunotherapy in thyroid ophthalmopathy
暂未订购
导出
摘要 目的 对比观察传统与新型免疫抑制剂对自身免疫性甲状腺眼病的疗效。方法  3 3例甲状腺眼病分别用糖皮质类固醇 (大、小剂量 )、雷公藤制剂或霉酚酸酯 (MMF)治疗 ,疗程 12~ 2 0周。结果 MMF组和大剂量糖皮质激素组有效率为 10 0 % ,其中MMF组显效比例高达 5 6。结论 MMF治疗甲状腺眼病疗效优于小剂量糖皮质激素和雷公藤总萜片。 Objective To compare the curative effects between the traditional and new immunosuppressants in autoimmune thyroid ophthalmopathy.Methods Thirty-three patients with thyroid ophthalmopathy were given glucocorticoid(higher or regular dose),tripterygium preparation,or mycophenolate mofetil(MMF)respectively.The therapeutic coures lasted for 12 to 20 weeks.Results The effective rates in MMF group and in higher-dose glucocorticoid group were 100%,and the proportion of remarkable improvement in MMF group was 5/6.Conclusion MMF may be more effective than glucocorticoid and tripterygium preparation in regular dose in the treatment of thyroid ophthalmopathy.
出处 《河北医药》 CAS 2000年第6期420-421,共2页 Hebei Medical Journal
关键词 甲状腺眼病 免疫治疗 霉酚酸酯 糖皮质类固醇 thyroid ophthalmopathy immunotherapy mycophenolate mofetil glucocorticoid tripterygium preparation
  • 相关文献

参考文献1

二级参考文献4

共引文献97

同被引文献45

  • 1岳式君,单忠艳,旷劲松,韩军星.大剂量激素冲击疗法治疗浸润性突眼[J].中国医科大学学报,1996,25(3):316-317. 被引量:14
  • 2顾锋,白耀,郭芝生,戴为信,吕朝,杜源耀.环孢素A治疗重症Graves眼病的临床观察[J].中华内分泌代谢杂志,1996,12(4):242-243. 被引量:16
  • 3Allison AC,Eugui EM.Mycophenolate mofetil and its mechanisms of action[J].lmmunopharmacology,2000,47(2-3):85-118.
  • 4Sievers TM,Rossi SJ,Ghobrial RM et al.Mycophenolate mofetil[J].Pharmacotherapy,1997,17:1178.
  • 5Kung AW, Michon J, Tai KS, et al. The effect of somatostatin versus corticosteroid in the treatment of Graves' ophthalmopathy[ J ]. Thyroid,1996,6(5) :381-384.
  • 6Bartalena L, Mareocci C, Bogazzi F, et al. Relation between therapy for hyperthyroidism and the course of Graves' ophthalmopathy[ J]. N Engl J Med, 1998,338(2) :73-78.
  • 7Hatton MP, Rubin PA. The pathophysiology of thyroid-associated ophythalmopathy[ J ]. Ophthalmol Clin North Am, 2002, 15 ( 1 ) : 113-119.
  • 8Perros P, Crombie AL, Kendall-Taylor P. Natural history of thyroid-associated ophthalmopathy[ J]. J Clin Endocrinol, 1995,42( 1 ) :45-50.
  • 9Pinchera A, Wiersinga WM, Glinoer D, et al. Classification of eye changes of Graves' disease[ J ]. Thyroid, 1992,2 (4) : 235.
  • 10Macchia PE, Bagattini M, Lupoli G, et al. High-dose intravenous corticosteroid therapy for Graves' ophthalmopathy[ J]. J Endocrinol Invest,2001,24(3) : 152-158.

引证文献3

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部