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结直肠癌循环肿瘤细胞临床应用进展 被引量:4

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摘要 结直肠癌是最常见的恶性肿瘤之一。在原发灶的早期阶段以及手术和化疗后,癌细胞可进入血液、形成远处转移灶,导致治疗效果差、预后不良。如果在转移灶形成之前能够在血液中发现循环肿瘤细胞(CTCs)则可早期发现转移倾向,同时为治疗期间监测治疗效果、判断预后提供有效数据,因而,能否有效地检测出结直肠癌CTCs直接关系到预后。目前开发更加特异、敏感的CTCs分子标记物以及更加高效的CTCs检测技术,对于提高结直肠癌CTCs的检出率具有重要的临床应用价值。本文就结直肠癌CTCs检测及临床应用做一综述。
作者 刘平 魏子白
出处 《现代肿瘤医学》 CAS 2013年第6期1393-1395,共3页 Journal of Modern Oncology
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