期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

阵发性睡眠性血红蛋白尿症诊断及治疗专家共识解读 被引量：7

原文传递
导出
摘要 我国阵发性睡眠性血红蛋白尿症（PNH）的诊断与治疗已取得显著进步，但该病的总体病死率尚无明显改观，因此进一步提高疗效面临严峻挑战，规范PNH诊疗，对提高其总体疗效和改善患者预后具有重要意义。中华医学会血液学分会红细胞疾病（贫血）学组在广泛征求有关专家意见的基础上，参考国内外有关文献，依据循证医学证据，进行深入研讨，达成我国PNH诊疗共识[1]。现将该共识解读如下。
作者 付蓉 李丽燕
机构地区 天津医科大学总医院血液科
出处 《中华医学杂志》 CAS CSCD 北大核心 2013年第20期1521-1523,共3页 National Medical Journal of China
关键词 阵发性睡眠性血红蛋白尿症 专家意见 解读 治疗 诊断 循证医学证据 总体疗效 红细胞疾病
分类号 R7 [医药卫生—临床医学] R5 [医药卫生—内科学]
  • 相关文献

参考文献7

  • 1中华医学会血液学分会红细胞疾病(贫血)学组.阵发性睡眠性血红蛋白尿症诊断及治疗专家共识.中华血液学杂志,2013,34:276—279.
  • 2Borowitz MJ, Craig FE, Digiuseppe JA, et al. Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry. Cytometry B Clin Cytom, 2010,78:211-230.
  • 3Parker C, Omine M, Richards S, et al. Diagnosis and management of paroxysmal nocturnal hemoglobinuria. Blood, 2005,106:3699-3709.
  • 4Kelly R J, Hill A, Arnold LM, et al. Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficac,t and imoroved survival. Blood. 2011. 117: 6786-6792.
  • 5邵宗鸿,赵明峰,李克,刘鸿,张益枝,施均,何广胜,和虹,张泓,陈桂彬,储榆林,杨天楹.低剂量联合化疗对难治性、复发性阵发性睡眠性血红蛋白尿症的疗效观察[J].中国实用内科杂志,2000,20(10):607-609. 被引量：13
  • 6曹燕然,邵宗鸿,贾海蓉,孙娟,刘鸿,吴玉红,秦铁军,施均,白洁,何广胜,付蓉,赵明峰,涂梅峰,崔振珠,杨天楹.DA或HA方案治疗难治、复发性阵发性睡眠性血红蛋白尿症的初步观察[J].中华血液学杂志,2004,25(4):202-204. 被引量：17
  • 7Taniguchi K, Okada M, Yoshihara S, et al. Strategy for bone marrow transplantation in eculizumab-treated paroxysmal nocturnal hemoglobinuria. Int J Hematol ,2011,94 :403407.

二级参考文献9

  • 1张之南，血液病诊断及疗效标准（第2版），1998年，88页
  • 2邵宗鸿，中华血液学杂志，1997年，18卷，10期，544页
  • 3Karadimitris A, Luzzatto L. The cellular pathogenesis of paroxysmal nocturnal hemoglobinuria. Leukemia,2001,15:1148-1152.
  • 4Alfinito F,lo Pardo C, Boccuni P, et al. Reliable identification of the PNH defect on lymphocyte and monocyte membrane by CD48 MoAbs, In:Kishimoto T, Kikutani I I, von dem Borne AEG, et al. eds. Leukocyte Typing Ⅵ. New York: Garland Publishing, 1997. 512
  • 5Rosti V, Tremml G, Soares V, et al. Embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion.J Clin Invest,1997,100:1028-1036.
  • 6Taylor VC,Sims M, Brett S, et al. Antibody selection against CD52 produces a paroxysmal nocturnal haemoglobinuria phenotype in human lymphocytes by a novel mechanism. Biochem J,1997,322:919-925.
  • 7Boccuni P,del Vecchio L,di Noto R,et al. Glycosyl-phosphatidylinositol (GPI)-anchored molecues and the pathogenesis of paroxysmal nocturnal hemoglobinuria. Crit Rev Oncol Hematol, 2000,33:25-43.
  • 8Araten DJ, Nafa K, Pakdeesuwan K,et al.Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals. Proc Natl Acad Sci U S A,1999,96:5209-5214.
  • 9邵宗鸿,赵明峰,李克,刘鸿,张益枝,施均,何广胜,和虹,张泓,陈桂彬,储榆林,杨天楹.低剂量联合化疗对难治性、复发性阵发性睡眠性血红蛋白尿症的疗效观察[J].中国实用内科杂志,2000,20(10):607-609. 被引量：13

共引文献21

同被引文献36

  • 1Ruiz-Delgado GJ,Vázquez-Garza E,Méndez-Ramírez N,et al.Abnormalities in the expression of CD55and CD59surface molecules on peripheral blood cells are not specific to paroxysmal nocturnal hemoglobinuria[J].Hematology,2009,14:33-37.
  • 2Parker C, Omine M, Richards S, et al. Diagnosis and management of paroxysmal nocturnal hemoglobinuria[J]. Blood. 2005, 106 3699-7O9.
  • 3Melo A, Carvalho RG, Amaral J, et al. Clinical management of paroxysmal nocturnal haemoglobinuria in pregnancy:three case reports[J]. Blood Transfus. 2011, 9:99-103.
  • 4Ziakas PD, Poulou LS, Rokas GI, et al. Thrombosis in paroxysmal nocturnal hemoglobinuria: sites, risks, outcome. An overview[J]. J Thromb Haemost. 2007, 5 : 642-5.
  • 5Ray JG, Burows RF, Ginsberg JS, et al. Paroxysmal nocturnal hemoglobinuria and the risk of venous thrombosis: review and recommendations for management of the pregnant and nonpregnant patient[J]. Haemostasis. 2000, 30:103-17.
  • 6Higgins SP, McMahon LP, Brennecke SP. Paroxysmal nocturnal haemoglobinuriainpregnancy--not to be confused withpre-eciampsla or Itl~LLI-' syndrome [J]. J Obstet Gynaecol. 2004, 24 (1) : 83-5.
  • 7Fieni S, Bonfanti L, Gramellini D, et al. Clinical management of paroxysmal hemoglobinuria in pregnancy: a case report and updated review[J].Obstet Gynecol Surv. 2006,61: 593-601.
  • 8Hall C, Richards S, Hillmen P. Primary prophylaxis with warfarin prevents thrombosis in paroxysmal nocturnal hemoglobinuria (PNH) [J]. Blood. 2003 Nov 15, 102(10) : 3587-91.
  • 9de Guibert S, Peffault de Latour R, Varoqueaux N, et al. Paroxysmal nocturnal hemoglobinuria and pregnancy before the eculizumab era: the French experience[J]. Haematologica.2011 Sep, 96 (9) : 1276-83.
  • 10Danilov AV, Brodsky RA, Craigo S, et al. Managing a pregnant patient with paroxysmal nocturnal hemoglobinuria in the era of eculizumab[J]. Leuk Res. 2010 May, 34 (5) :566-71.

引证文献7

二级引证文献11

中华医学杂志
2013年 第20期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部