摘要
背景:疣状胃炎是一种特殊类型的慢性胃炎,目前尚无特异性治疗方法。目的:探讨氩离子凝固术(APC)治疗疣状胃炎的疗效。方法:选取2010年9月～2012年7月上海市青浦区朱家角人民医院经内镜检查确诊的疣状胃炎患者65例,随机分为治疗组和对照组。幽门螺杆菌(Hp)阳性者先行四联疗法根除Hp。治疗组患者行APC治疗后给予质子泵抑制剂(PPI)和胃黏膜保护剂治疗8周,对照组接受PPI和胃黏膜保护剂治疗8周。比较两组的治疗效果。结果:经APC治疗后,患者临床症状明显改善。治疗组的病灶数目减少程度明显高于对照组(P<0.05)。22例对照组患者药物治疗疗效不明显,转组接受APC治疗后,病灶数目显著降低(P<0.05)。结论:APC可有效治疗疣状胃炎,且安全性良好。
Background： Verrucous gastritis is a special type of chronic gastritis without specific treatment. Aims ： To investigate the effect of argon plasma coagulation （APC） in verrucous gastritis. Methods： Sixty-five patients with verrucoas gastritis diagnosed by endoscopy from September 2010 to July 2012 at Zhujiajiao People＇ s Hospital of Qingpu District were enrolled and randomly divided into treatment group and control group. All Helicobacter pylori （Hp） -positive patients were given quadruple therapy to eradicate Hp. Patients in treatment group had APC performed followed by proton pump inhibitor （PPI） combined with gastric mucosal protectant for 8 weeks, and patients in control group only received PPI combined with gastric mucosal protectant for 8 weeks. The therapeutic efficacy between the two groups was compared. Results： Clinical symptoms were ameliorated in patients with verrucous gastritis after treatment with APC. The decreased number of lesion was significantly higher in treatment group than in control group （P 〈 0.05 ）. Twenty-two patients in control group also received APC because the efficacy of medical treatment was not satisfactory, and after APC the number of lesion was significantly decreased （P 〈 0.05）. Conclusions： APC is an effective and safe therapeutic tool for verrucous gastritis.
出处
《胃肠病学》
2013年第5期301-303,共3页
Chinese Journal of Gastroenterology
关键词
疣状胃炎
氩离子凝固术
螺杆菌
幽门
治疗
Verrucous Gastritis
Argon Plasma Coagulation
Helicobacter pylori
Therapy
