细胞因子信号与核定位——JAK-STAT途径新进展
被引量：1
摘要
细胞因子的信号转导JAK STAT途径是当前研究的热点。本文以IFN γ为例 ,阐述了细胞因子和 或受体作为伴侣分子 ,与STAT一起发生核转位 ,并共同调控基因的表达 ,为JAK
出处
《国外医学（免疫学分册）》
CAS
2000年第3期131-134,共4页
Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
同被引文献19
-
1Matsumoto S,Nanno M,Watanabe N,et al.Physiological roles of gammadelta T-cell receptor intraepithelial lymphocytes in cytoproliferation and differentiation of mouse intestinal epithelial cells[J].Immunology,1999,97(1):18-25.
-
2Hess DJ,Henry-Stanley MJ,Erickson EA,et al.Effect of tumor necrosis factor alpha,interferon gamma,and interleukin-4 on bacteria-enterocyte interactions[J].J Surg Res,2002,104(2):88-94.
-
3Zachrisson K,Neopikhanov V,Samali A,et al.Interleukin-1,interleukin-8,tumournecrosis factor alpha and interferon gamma stimulate DNA synthesis but have no effect on apoptosis in small-intestinal cell lines[J].Eur J Gastroenterol Hepatol,2001,13(5):551-559.
-
4Bruewer M,Luegering A,Kucharzik T,et al.Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms[J].J Immunol,2003,171(11):6164-6172.
-
5Dignass AU,Podolsky DK.Cytokine modulation of intestinal epithelial cell restitution:central role of transforming growth factor beta[J].Gastroenterology,1993,105(5):1323-1332.
-
6Abreu MT,Arnold ET,Thomas LS,et al.TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells[J].J Biol Chem,2002,277(23):20431-20437.
-
7Salmenpera P,Hamalainen S,Hukkanen M,et al.Interferon-gamma induces C/EBP beta expression and activity through MEK/ERK and p38 in T84 colon epithelial cells[J].Am J Physiol Cell Physiol,2003,284(5):C1133-C1139.
-
8O'Loughlin EV,Pang GP,Noltorp R,et al.Interleukin 2 modulates ion secretion and cell proliferation in cultured human small intestinal enterocytes[J].Gut,2001,49(5):636-643.
-
9Dignass AU,Podolsky DK.Interleukin 2 modulates intestinal epithelial cell function in vitro[J].Exp Cell Res,1996,225(2):422-429.
-
10Shea-Donohue T,Sullivan C,Finkelman FD,et al.The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial cell function[J].J Immunol,2001,167(4):2234-2239.
二级引证文献2
-
1刘文跃,王琳,王建峰,席红卫.小儿急性肠梗阻肠黏膜免疫屏障损伤及细菌移位的研究[J].中华小儿外科杂志,2011,32(8):577-580. 被引量：18
-
2李洋,宋志前,鲁欣悦,王淳,彭诗涛,张婷,宁张弛.溃疡性结肠炎的肠道免疫研究进展[J].中国中医基础医学杂志,2024,30(1):168-175. 被引量：14
-
1刘飞.细胞因子信号传导JAK-STAT途径的研究进展[J].细胞与分子免疫学杂志,1997,13(1):62-65. 被引量：2
-
2李贵新.JAK-STAT途径[J].国外医学（免疫学分册）,1997,20(6):329-331. 被引量：1
-
3陈建忠,朱海红,陈智,刘克洲.IFN-α/β信号传导研究进展[J].国外医学（流行病学．传染病学分册）,2003,30(5):266-268. 被引量：7
-
4王俐,谭锦泉.STAT调控机制研究进展[J].现代免疫学,2005,25(1):78-81. 被引量：7
-
5孙凯.细胞因子受体中的共用链现象及信号转导[J].免疫学杂志,1996,12(2):131-135. 被引量：2
-
6赵朴,郑玉姝,贾贝贝,刘兴友,姚四新.微RNA:天然免疫的新型调节子[J].生命的化学,2008,28(5):540-543.
-
7白莉,余祖滨,钱频,钱桂生,关崧,李淑萍.SOCS 3基因对缺氧肺动脉平滑肌细胞增殖及原癌基因mRNA表达的影响[J].中华内科杂志,2005,40(1):42-45. 被引量：9
-
8牟芝蓉,吴玉章.MHCⅠ类分子在内质网中的组装研究进展[J].免疫学杂志,2001,17(z1):1-4.
-
9邱莲女,马志章.细胞信号转导JAK-STAT途径的研究进展[J].国外医学（分子生物学分册）,1998,20(1):14-17.
-
10张奇,吴健,于波.SOCS1与免疫调节的研究进展[J].免疫学杂志,2010,26(11):1008-1011. 被引量：5
