摘要
目的探讨早期胃癌淋巴结转移的危险因素,研究早期胃癌淋巴结转移与临床病理因素的关系。方法根据术中探查发现及术后病理结果确诊,将215例早期胃癌患者分为淋巴结转移组(36例)和无淋巴结转移组(179例),对2组患者的临床病理资料进行回顾性分析。结果 2组患者性别、年龄、肿瘤部位、肿瘤类型、分化程度比较差异均无统计学意义(均P>0.05);肿瘤浸润深度、肿瘤最大直径和幽门螺杆菌(Hp)感染2组比较差异均有统计学意义(均P<0.05)。Logistic多因素回归分析显示:肿瘤浸润深度与早期胃癌淋巴结转移的发病有关(OR=3.103,95%CI:1.495～6.609)。结论肿瘤的浸润深度是影响早期胃癌淋巴结转移的独立危险因素。
Objective To investigate the risk factors for lymph node metastasis in patients with early gastric cancer, and to explore the relationship between lymph node metastasis from early gastric cancer and clinical pathological factors. Methods According to intraoperative findings and postoperative pathological results, 215 patients with early gastric cancer were divided into lymph node metastasis group （n=36）and non-metastasis group （n=179）. Clinical and pathological data of patients were analyzed retrospectively. Results There were no significant differences in gender, age, tumor location, tumor type and differentiation degree between the two groups （P〉0.05）. However, the differences in tumor invasion depth, maximum tumor diameter and Helicobacter pylori infection were obvious between the two groups （P〈0.05）. Multivariable logistic regression analysis revealed that tumor invasion depth was correlated with lymph node metastasis in patients with early gastric cancer （OR= 3.103, 95%CI=1.495-6.609）. Conclusion Tumor invasion depth is an independent risk factor for lymph node metastasis in patients with early gastric cancer.
出处
《实用临床医学（江西）》
CAS
2013年第3期46-48,74,共4页
Practical Clinical Medicine
关键词
早期胃癌
淋巴结转移
危险因素
early gastric cancer
lymph node metastasis
risk factors
