摘要
目的探讨乌司他丁在炎性肠梗阻治疗中的应用效果。方法将60例炎性肠梗阻患者随机分为观察组和对照组,每组30例。对照组给予常规治疗措施,观察组在此基础上给予乌司他丁治疗,评估两者治疗效果。结果观察组患者腹痛、腹胀消失时间以及肛门排气时间均短于对照组,2组比较差异具有统计学意义(P<0.05)。2组治疗后患者血清IL-6、IL-8及TNF-α水平较治疗前均明显降低(P<0.05);治疗后观察组患者IL-6、IL-8及TNF-α水平均显著低于对照组(P<0.05)。结论乌司他丁治疗炎性肠梗阻的疗效确切,值得应用。
Objective To Methods Sixty patients with investigate the inflammatory effect of ulinastatin on inflammatory intestinal obstruction. intestinal obstruction were randomly given conventional treatment （control group, n=30） or in combination with ulinastatin treatment （observation group, n=30）. Curative effects were evaluated in both groups. Results Compared with the levels before treatment, serum IL-6, IL-8 and TNF-ct significantly decreased after treatment （P〈0.05）. Compared with control group,the time to abdominal pain disappearance, abdominal distention disappearance and anal exhaust and serum levels of IL-6, IL-8 and TNF-ct obviously decreased in observation group （P〈0.05）. Conclusion Ulinastatin has obvious curative effect and is worth being used in patients with inflamm- atory intestinal obstruction.
出处
《实用临床医学（江西）》
CAS
2013年第3期44-45,60,共3页
Practical Clinical Medicine
关键词
乌司他丁
炎性肠梗阻
疗效
ulinastatin
inflammatory intestinal obstruction
effect
