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帕瑞昔布钠在术后镇痛中的应用进展 被引量:7

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摘要 非甾体抗炎药(NSAIDs)通过抑制环氧化酶(COX),以减少花生四烯酸(AA)转化成前列腺素(PGs)等炎症介质,达到抗炎镇痛的目的,是目前疼痛治疗的常用药物。非选择性的NSAIDs大部分都是口服型药物,虽能同时阻断COX-1和COX-2,起到抗炎和止痛作用,由于对胃肠道、心血管、肾脏和血小板等的不良反应限制了其在术后急性疼痛中应用,并且对于术后恶心、呕吐以及不能口服药物的病人也不是理想选择。
作者 宋德玲
出处 《黑龙江医药》 CAS 2013年第3期481-482,共2页 Heilongjiang Medicine journal
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同被引文献64

  • 1窦东梅,张永乐,李瑞玲.不同术式对高龄髋部骨折患者术后发生谵妄的影响[J].中国老年学杂志,2014,34(4):1088-1089. 被引量:17
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