摘要
目的:建立香枫舒颗粒的质量标准。方法:采用薄层色谱(TLC)法定性鉴别香枫舒颗粒中白术、金钱草、广藿香;用高效液相色谱法测定广藿香中毛蕊花糖苷的含量。结果:TLC斑点清晰、分离度好,阴性对照无干扰。毛蕊花糖苷的进样量在0.042～0.350μg范围内与其峰面积积分值呈良好的线性关系(r=0.9999);精密度、稳定性、重复性试验的RSD均<1%;平均加样回收率为98.40%,RSD=0.66%(n=9)。结论:所建标准可用于香枫舒颗粒的质量控制。
OBJECTIVE： To establish the quality standard of Xiangfengshu granules. METHODS： TLC method was used to qualitatively identify Atractylodes macrocephala,Lysimachia christinae, Pogostemon cablin; the content of verbascoside in P cablin was determined by HPLC. RESULTS： TLC sports were fairy clear and well-separated without interference form negative control. The linear range of verbascoside was 0.042-0.35 μg （r=0.999 9） with average recovery of 98.40% （RSD=0.66% ,n=9）. RSDs of precision, stability and reproducibility tests were all lower than 1%. CONCLUSIONS： Established standard is suitable for the quali-ty control of Xiangfengshu granules.
出处
《中国药房》
CAS
CSCD
2013年第23期2177-2179,共3页
China Pharmacy
关键词
香枫舒颗粒
质量标准
白术
金钱草
广藿香
毛蕊花糖苷
薄层色谱法
高效液相色谱法
Xiangfengshu granules
Quality standard
Atractylodes macrocephala
Lysimachia christinae
Pogostemon cab-lin
Verbascoside
TLC
HPLC
