摘要
目的:比较经皮经肝胆管引流术(PTCD)内外联合引流术与单纯外引流术治疗恶性梗阻性黄疸的疗效及并发症。方法:回顾性分析我院恶性梗阻性黄疸病例78例,分析采用不同术式的两组病例术前术后血清总胆红素、白蛋白、白细胞总数的水平变化。结果:两组病例术后第3天及第1个月血清总胆红素下降水平较术前差异有统计学意义。两组病例术前术后血清白蛋白变化差异均无统计学意义,术后1个月白细胞总数较术前有所下降,但多数未达到正常水平,且两组之间差异有统计学意义。结论:内外联合引流术早期降黄效果优于单纯外引流术,1个月后两者的降黄效果相当。PTCD术后的早期感染可能与操作本身相关,而后期的感染则可能与胆汁返流相关。
Objective To compare the efficacy and complications of internal and external combined drainage PTCD and single external drainage for treating malignant obstructive jaundice. Methods Retrospective analysis 78 cases of malignant obstructive jaundice, and compare the serum total bilirubin, albumin and total number of white blood cells in two groups. Results Serum total bilirubin level in two groups decreased significantly after I^CD treatment. Serum bilirubin in combined drainage group decreased significantly than that in single external drainage group 3 days after PTCD. There arc no significant changes in serum albumin in the two groups. After one month, the decreased white blood cells were improved, but most have not reached normal levels. There were statistically significant differences between the two groups. Conclusions The effect of early drop jaundice with internal and external combined drainage is better than that with single external drainage, but after 1 nonth, two guoups had same effect. Early infection post PTCD may be related with operation itself, and later infection may be associated with bile regurgitation.
出处
《实用医学杂志》
CAS
北大核心
2013年第11期1762-1764,共3页
The Journal of Practical Medicine
基金
国家自然科学基金项目(编号:81241132)
教育部博士学科点专项科研基金项目(编号:20120171120086)
