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全基因组关联分析在水稻遗传育种中的应用 被引量：14

Application of Genome-wide Association Studies in Rice Genetics and Breeding
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摘要 关联分析是解析作物表型多样性遗传基础的有效工具,也是挖掘有利等位基因的重要手段,在作物遗传育种中发挥着越来越重要的作用。随着挖掘覆盖全基因组的单核苷酸多态性(Single nucleotide polymorphisms,SNP)标记技术的不断改进,基于连锁不平衡(Linkage disequilibrium,LD)的全基因组关联分析为研究作物的农艺、品质、产量和抗性等复杂性状提供了新途径。本文在系统介绍全基因组关联分析方法的基础上,详尽总结了其在水稻遗传育种中的研究进展,并探讨了其存在的潜在问题及解决途径。 Association mapping is widely used to dissect the genetic basis of phenotypic diversities and to mine the useful allele at a locus in plants or crops. With the technical development of mining the single nucleotide polymorphisms （SNP） in target genome, genome-wide association studies （GWAS） based on linkage disequilibrium （LD） offers a new method to analyze the genetic basis of the complex agronomic traits. In this paper, the method of GWAS and its application in rice are summarized, and the potential problems of using GWAS in plants are discussed.
作者 唐富福 徐非非 包劲松
机构地区 浙江大学原子核农业科学研究所 四川省原子能研究院
出处 《核农学报》 CAS CSCD 北大核心 2013年第5期598-606,共9页 Journal of Nuclear Agricultural Sciences
基金 公益性行业(农业)科研专项(201103007) 中央高校基本科研业务费专项(2011FZA6011)
关键词 全基因组关联分析 单核苷酸多态性 群体结构 基因型鉴定 水稻 Genome-wide association studies （GWAS）Genotyping Rice Single nucleotide polymorphism （SNP） Population structure
分类号 S511 [农业科学—作物学]
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参考文献49

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二级参考文献231

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共引文献126

同被引文献192

引证文献14

二级引证文献109

核农学报
2013年 第5期

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