期刊文献+

降钙素原检测在慢性阻塞性肺疾病急性加重期的临床意义 被引量:3

The Clinical Significance of Procalcitonin in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
暂未订购
导出
摘要 目的探讨降钙素原(PCT)检测在慢性阻塞性肺疾病患者急性加重期的临床意义。方法入选87例慢性阻塞性肺疾病患者,其中18例稳定期患者作为稳定组,69例急性期患者分为单纯组(22例)和肺炎组(47例)。对患者的白细胞计数、PCT、痰培养结果、住院时间等进行分析比较。结果肺炎组患者住院时间和白细胞计数高于单纯组,差异有统计学意义(P<0.05)。3组PCT水平比较,差异有统计学意义(P<0.05),肺炎组最高,稳定组最低。结论血清PCT能反映慢性阻塞性肺疾病不同时期炎症程度,指导临床治疗。 Objective To evaluate the clinical significance of procalcitonin(PCT) in patients of acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods 87 patients with COPD,including 18 cases of patients with stable as the stable group,69 cases of acute period were divided into control group(22 cases) and pneumonia group(47 cases).The white blood cell(WBC),PCT,and microbiological findings in each group were compared.Results Pneumonia and white blood cell count in patients was significantly higher than control group,the difference was statistically significant(P〈0.05).Comparison of level of PCT in the 3 groups,the difference was statistically significant(P〈0.05),pneumonia group was the highest,stable group was the lowest.Conclusion PCT level is valuable to differentiate the clinical status of COPD,and guide its treatment.
出处 《实用心脑肺血管病杂志》 2013年第6期20-21,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 降钙素原 肺疾病 慢性阻塞性 肺炎 Procalcitonin Pulmonary disease chronic obstructive Pneumonia
  • 相关文献

参考文献9

二级参考文献45

  • 1沈定霞,罗燕萍,崔岩,赵莉萍,白立彦.分离产金属β-内酰胺酶的铜绿假单胞菌[J].中华医院感染学杂志,2004,14(1):86-88. 被引量:109
  • 2刘又宁,陈民钧,赵铁梅,王辉,王睿,刘庆锋,蔡柏蔷,曹彬,孙铁英,胡云建,修清玉,周新,丁星,杨岚,卓建生,唐英春,张扣兴,梁德荣,吕晓菊,李胜歧,刘勇,俞云松,魏泽庆,应可净,赵峰,陈萍,侯晓娜.中国城市成人社区获得性肺炎665例病原学多中心调查[J].中华结核和呼吸杂志,2006,29(1):3-8. 被引量:792
  • 3有创-无创序贯机械通气多中心研究协作组.以肺部感染控制窗为切换点行有创与无创序贯机械通气治疗慢性阻塞性肺疾病所致严重呼吸衰竭的随机对照研究[J].中华结核和呼吸杂志,2006,29(1):14-18. 被引量:280
  • 4慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8235
  • 5Ngeow YF,Suwanjutha S,Chantarojanasriri T,et al.An Asian study on the prevalence of atypical respiratory pathogens in community-acquired pneumonia.Int J Infect Dis,2005,9:144-153.
  • 6de Roux A,Marcos MA,Garcia E,et al.Viral community-acquired pneumonia in nonimmunocompromised adults.Chest,2004,125:1343-1351.
  • 7Ostrosky-Zeichner L,Alexander BD,Kett DH,et al.Multicenter clinical evaluation of the (1→3) beta-D-glucan assay as an aid to diagnosis of fungal infections in humans.Clin Infect Dis,2005,41:654-659.
  • 8Food and Drug Administration,HHS.Class Ⅱ Special Controls Guidance Document:serological assays for the detection of betaglucan.Fed Reqist,2004,69:56934-56936.
  • 9Mandell LA,Marrie TJ,Grossman RF,et al.Canadian guidelines for the initial management of community-acquired pneumonia:an evidence-based update by the Canadian Infectious Diseases Society and the Canadian Thoracic Society.The Canadian CommunityAcquired Pneumonia Working Group.Clin Infect Dis,2000,31:383-421.
  • 10Woodhead M,Blasi F,Ewig S,et al.Guidelines for the management of adult lower respiratory tract infections.Eur Respir J,2005,26:1138-1180.

共引文献11391

同被引文献39

  • 1社区获得性肺炎诊断和治疗指南[J].中华结核和呼吸杂志,2006,29(10):651-655. 被引量:3119
  • 2慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8235
  • 3陈灏珠,林果为,王吉耀实用内科学[M].14版北京:人民卫生出版社:2013:9.
  • 4Guthfie R. Community - acquired lower respiratory tract infections : etiology and treatment [J]. Chest, 2001, 120 (6) : 2021 -2034.
  • 5Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008 [J]. Crit Care Med, 2008, 36 (1) : 296 - 327.
  • 6Katan M, Mailer B, Christ -Crain M. Copeptin: a new and promising diagnostic and prognostic marker [ J ]. Crit Care, 2008, 12 (2): 117.
  • 7Muller B, Morgenthaler N, Stolz D, et al. Circulating levels of eopeptin, a novel biomarker, in lower respiratory tract infections [J]. EurJ Clin Invest, 2007, 37 (2) : 145 -152.
  • 8Albrich WC, Dusemund F, Bucher B, et al. Effectiveness and Safety of Procalcitonin - Guided Antibiotic Therapy in Lower Respiratory Tract Infections in " Real Life ": An International, Multicenter Poststudy Survey (ProREAL) [ J]. Arch Intern Med, 2012, 172 (9): 715-722.
  • 9Agarwal R, Schwartz DN. Procalcitonin to guide duration of antimicrobia| therapy in intensive care units: a systematic review [J]. Clin Infect Dis, 2011, 53 (4) : 379 -387.
  • 10中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病疾病诊治指南[J].中华内科学杂志,2007,46(3):254-261.

引证文献3

二级引证文献34

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部