摘要
目的探讨2型糖尿病合并早期肾病患者微量清蛋白尿的患病率及其与心血管疾病危险因素的关系。方法以2009年3月—2011年3月住院的130例2型糖尿病患者为研究对象,将患者分为两组:合并微量清蛋白尿者为A组,未合并微量清蛋白尿者为B组。对两组患者的左心室质量指数(left ventricular mass index,LVMI)、体质指数(body mass index,BMI)、糖化血红蛋白(HbA1c)、血脂和颈动脉内膜中层厚度(intima-media thickness,IMT)进行测定。结果 130例患者中微量清蛋白尿的患病率为32.3%,其中男女患病率比较,差异无统计学意义(P>0.05)。A、B两组患者年龄、糖尿病病程、血压、LVMI、HbA1c、平均IMT比较,差异均有统计学意义(P<0.05)。结论 2型糖尿病合并微量清蛋白尿患者的LVMI、IMT、BMI、糖尿病病程明显高于尿蛋白阴性患者,医务人员对糖尿病肾病早筛查早干预可预防心血管疾病的发生。
Objective To discuss the relationship between the prevalence of type 2 diabetes with early nephropathy patients with microalbuminuria and factors and risk of cardiovascular disease.Methods In March 2009 to March 2011,130 patients with type 2 diabetes hospitalized as the object of study,the patients were divided into two groups：combined with microalbuminuria as A group and no complicated with microalbuminuria to group B.On left ventricular mass index of the patients in the two groups（left ventricular mass index,LVMI）,body mass index（BMI）,glycosylated hemoglobin（HbA1c）,blood lipid and carotid artery intima-media thickness（IMT） were measured.Results 130 patients with microalbuminuria prevalence rate was 32.3%,the rate in male and female,the difference was not statistically significant（P〈0.05）.A,B two groups of patients with age,duration of diabetes,LVMI,HbA1c,average IMT,the differences were statistically significant（P〈0.05）.Conclusion Type 2 diabetic patients with microalbuminuria were LVMI,IMT,BMI,duration of diabetes was significantly higher than that of urine protein negative patients,medical staff on diabetic nephropathy early screening early intervention can prevent the occurrence of cardiovascular disease.
出处
《实用心脑肺血管病杂志》
2013年第6期14-15,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金
河北省科技厅科技支撑计划项目(12277779)
关键词
微量清蛋白尿
糖尿病
2型
心血管疾病
危险因素
Microalbuminuria
Diabetes mellitus
type 2
Cardiovascular diseases
Risk fator
