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抗心磷脂抗体与脑血管病相关性研究 被引量:11

The study of relationship between anticardiolipin antibodyand cerebrovascular diseases
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摘要 目的 :研究抗心磷脂抗体 (ACA)与脑血管病的关系 ,为脑卒中的预测提供临床依据。方法 :采用前瞻性研究方法 ,对 91例脑梗死 (CI)、4 2例脑出血 (CH)患者及 30例健康者血清中的抗心磷脂抗体 (ACA)进行检测。结果 :CI及 CH组 ACA总阳性率、Ig G型 ACA阳性率均显著高于对照组。ACA阳性卒中容易复发 ,病灶常为多个。ACA在脑卒中发病一周内阳性率最高 ,且抗体分型以 Ig G型为主。结论 :ACA是 CI及 CH的危险因素 。 Objective:To Study the relationship between cerebral vescular diseases and anticardiolipin antibody for providiy a clinical evidence for stroke prediction Methods:Serum ACA was measured in 91 patients with cerebral infarction(CI),42 patients with cerebral hemorrhage(CH)and 30 control subjects.Results:The prenalence of ACA in CI and CH patients was different significantly compared with control and IgG ACA was a most important isotype.Stroke in ACA positive group tended to be recurrent and multiple event.Positive rate of IgG ACA reached its climax within the first week after stroke onset.Conclusion:The results suggested ACA be an independent risk factor in CI and CH and ACA was valuable in stroke prediction.
出处 《卒中与神经疾病》 2000年第2期104-106,共3页 Stroke and Nervous Diseases
关键词 抗心磷脂抗体 脑梗死 脑出血 Anticardiolipin antibody Cerebral infarction Cerebral hemorrhage
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  • 2郝静,韩丹春.动态监测脑血管病患者抗心磷脂抗体及 ENA 多肽抗体的临床意义[J].临床神经病学杂志,1997,10(1):18-20. 被引量:12
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