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急性髓系白血病患者微小残留病检测的研究进展 被引量：1

Research progress of assessment of minimal residual disease in acute myeloid leukemia
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摘要 近年来，随着多参数流式细胞术（MFC）及荧光实时定量聚合酶链反应（RQ—PCR）检测手段的进步，两者越来越多地被应用于急性髓系白血病（AML）患者微小残留病（MRD）的检测。通过这些更加客观、敏感及特异的检测方法的应用，将更有助于评估AML的疗效及监测早期复发，并可据此调整治疗策略。 Assessment of minimal residual disease （MRD） in acute myeloid leukemia （AML） patients is now possible by using updated methods including real-time quantitative PCR （RQ-PCR） for abnormal fusion transcripts and multiparameter flow cytometry （MFC） for detecting leukemia-associated phenotypes. Using these techniques, MRD analysis has shown value in terms of risk assessment, continued patient monitoring, and therapeutic decision-making.
作者 薛华(综述) 化罗明(审校)
机构地区 河北大学附属医院血液科
出处 《白血病．淋巴瘤》 CAS 2013年第5期318-320,共3页 Journal of Leukemia & Lymphoma
关键词 白血病 髓样 急性 微小残留病 Leukemia, myloid, acute Minimal residual disease
分类号 R733.7 [医药卫生—肿瘤]
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参考文献30

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同被引文献19

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白血病．淋巴瘤
2013年 第5期

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