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急性胰腺炎并发肝损害的临床研究 被引量:6

Clinical study of acute pancreatitis complicated with liver damage
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摘要 目的:探讨和分析急性胰腺炎(AP)并发肝损害的临床特点及对预后的影响。方法:对106例AP患者的临床资料进行分析,了解肝损害的发生率,肝损害的程度对病程的影响。结果:106例AP患者中有63例合并肝损害,其中重症胰腺炎(SAP)35例,轻症胰腺炎(MAP)28例;胆源性胰腺炎(BAP)54例,非胆源性胰腺炎(NBAP)9例。SAP较MAP肝损害发生率高(分别为100%和39.4%),BAP比NBAP肝损害发生率高(分别为80.6%和23.1%)。SAP肝功能损害较MAP重,差异有显著性(P<0.05)。SAP合并肝功能损害的患者,其腹痛缓解时间,血淀粉酶复常时间及住院天数均较MAP合并肝功能损害的患者明显延长(P<0.05)。结论:急性胰腺炎并发肝损害可影响病情的发展及预后。 Objective. To investigat e and analyze the clinical features of acute pancreatitis (AP) com- impact on prognosis. Methods: 106 cases of AP patients clinical incidence rate and the effect of the degree of liver damage on path- es of AP patients, 63 cases were with liver damage, including 35 plicated with liver damage and its data were analyzed to explore the ogenesis. Results: In the 106 cas cases of severe acute pancreatitis (SAP) and 28 cases of mild pancreatitis (MAP) ~ In the 54 cases of gallstone pancreatitis (BAP) and 9 cases of non-gallstone pancreatitis (NBAP). The incidence of liver damage in the SAP group (100%) was higher than that in the MAP group(39.4%) ;and the incidence of liver damage in the BAP group (80.6%) was higher than the NBAP group (23.1%). The degree of liver damage in the SAP group was severer than that in the MAP group, which was significant different (P〈0.05). The abdominal pain time, time to normalization of serum amylase and hospital stay were longer in SAP patients complicated with liver damage than those in MAP pa- tients complicated with liver damage (P〈0.05). Conclusion. Acute pancreatitis complicated with liver damage can affect the development and prognosis of the disease.
出处 《华夏医学》 CAS 2013年第1期21-23,共3页 Acta Medicinae Sinica
关键词 急性胰腺炎 肝损害 预后 acute pancreatitis liver damage prognosis
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