摘要
目的 探讨踝臂指数（ABI）联合超敏C反应蛋白（hs-CRP）检测对评价糖尿病患者冠状动脉病变的价值。方法 238例糖尿病患者根据256层极速CT诊断结果分为无冠脉病变组52例、轻度冠脉病变组103例、严重冠脉病变组83例。检测所有患者的ABI和hs-CRP,并分析合并冠脉病变患者ABI、hs-CRP与颈动脉内膜中层厚度（IMT）的关系。结果 轻度病变组、严重病变组与无病变组ABI、hs-CRP差异均有统计学意义（P〈0.05或P〈0.01）,严重病变组与轻度病变组的ABI、hs-CRP差异亦均有统计学意义（均P〈0.05）。合并冠脉病变患者IMT为（1.37±0.29）mm,与ABI呈负相关关系（r=－0.2195,P〈0.05）,与hs-CRP呈正相关关系（r=0.3946,P〈0.05）。结论 ABI、HS-CRP的水平变化与冠脉病变密切相关。
Objective To explore the clinical value of the detection of ankle-brachial index（ABI） combined with high-sensitivity C-reactive protein（hs-CRP） for evaluation coronary artery lesions in diabetic patients.Methods According to the diagnostic results of 256 layer speed CT,238 diabetic patients were divided into the group without coronary artery lesions（52 cases）,the group with mild coronary artery lesions（103 cases） and the group with severe coronary artery lesions（83 cases）.The ABI and hs-CRP were detected.The relationship between ABI,hs-CRP and cartotid artery intima-media thickness（IMT） were analyzed.Results The ABI and hs-CRP of the group with mild coronary artery lesions or with severe coronary artery lesions were lower than that of the group without coronary artery lesions（P〈0.05 or P〈0.01）.The ABI and hs-CRP of the group with mild coronary artery lesions were lower than that of the group with severe coronary artery lesions（all P〈0.05）. The IMT was （1.37±0.29）mm in the group with coronary artery lesions,which had a negative correlation with ABI（r=-0.2195,P〈0.05） and a positive correlation with hs-CRP（r=0.3946,P〈0.05）.Conclusion The detection of ABI combined with hs-CRP can be used to evaluate diabetic patients with coronary artery disease.
出处
《中国基层医药》
CAS
2013年第11期1628-1630,共3页
Chinese Journal of Primary Medicine and Pharmacy
