摘要
目的探讨中医滋养肝肾方治疗儿童抽动障碍的临床疗效、安全性及其与过敏相关性。方法将本院收治的96例患有抽动障碍的患儿随机分为实验组和对照组,实验组患儿给予滋养肝肾方治疗,并根据患儿辨证给予加减;对照组患儿给予氟哌啶醇治疗,治疗完成后采用耶鲁综合抽动严重程度量表(YGTSS)进行评分,采用副反应量表(TESS)进行安全性评价,测量两组患儿IgE水平,比较两组患儿治疗有效率。结果实验组YGTSS、TESS、IgE分别为(19.3±5.9)分、(1.3±0.8)分、(189.4±154.3)IU/ml,有效率为85.4%;对照组YGTSS、TESS、IgE分别为(28.6±7.4)分、(11.2±6.4)分、(211.9±183.2)IU/ml,有效率为70.8%。实验组YGTSS、TESS均显著低于对照组(P<0.05),而有效率显著高于对照组(P<0.05),两组IgE无统计学差异(P>0.05)。结论儿童抽动障碍与过敏反应联系并不确切,而采用滋养肝肾方加减治疗儿童抽动障碍疗效显著,且安全性高。
Objective To explore the clinical efficacy and safety of liver and kidney nourishing treatment of traditional Chinese medicine for child tic disorder and its association with allergy. Methods Ninety-six children suffering from tic disorder admitted to our hospital were randomly divided into experimental group and control group. The experimental group was given liver and kidney nourishing treatment, while the control group was given haloperidol. Yale global tic severity scale （YGTSS） was adapted and the side effects scale （TESS） was used to evaluate the safety after the treatment. IgE level and treatment efficiency were compared be- tween the two groups after treatment had been completed. Results YGTSS, TESS, IgE and effective rate were （ 19.3 ± 5.9 ） points, （1.3 ± 0.8）points, （189.4 ± 154.3） IU/ml and 85.4% in the experimental group, and （28.6 ± 7.4）points, （11.2 ± 6.4） points, （211.9 ± 183.2） IU/ml and 70.8% in the control group, respectively. YGTSS and TESS were significantly lower and efficiency was significantly higher in the experimental group than in the control group （ P 〈 0.05 ）. There was no significant difference in IgE level between the two groups （ P 〉 0.05 ）. Conclusion Child tic disorder is not found to be exactly associated with allergic reaction. Liver and kidney nourishing treatment from traditional Chinese medicine is highly safe and effective on the disorder.
出处
《临床军医杂志》
CAS
2013年第5期506-507,510,共3页
Clinical Journal of Medical Officers
关键词
滋养肝肾方
抽动障碍
过敏反应
liver and kidney nourishing treatment
tic disorder
allergic reaction
