1Yuan TL,et al. PI3K pathway alterations in cancer:variations on a theme [ J ]. O ncogene, 2008,27 ( 42 ) : 5497 - 5510.
2Shmiamura H, Terada Y, Okado T, et al. The PI3 - kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro viaNF-kappa B and Bad[J]. J Am Soc Nephrol,2003,14 (6) :1427 - 1434.
3Persad S,Attwell S, Gray V,et al. Regulation of protein kinase B/ Akt- serine 473 phosphorylation by integrin-linked kinase: critical roles forkinase activity and amino acids arginine 211 and serine 343 [ J ]. J Biol Chem ,2001,276 (29) :27462 - 27469.
4Widmann C,Gibson S,Johnson GL. Caspase-depend-ent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti - apoptotic signals [ J ]. J Biol Chem, 1998,273 (12) :7141 - 7147.
5Hoch RV,Soriano P. Roles of PDGF in animal development[ J] Development ,2003,130 ( 20 ) :4769 - 4784.
9Heldin CH,Westermark B.Mechanism of action and in vivo role of platelet-derived growth factor[J].Physiol Rev.1999,79(4):1283~1316
10Inagami T,Kambayashi Y,Ichiki T,et al,Angiotensin Ⅱ receptors AT1 and AT2:new mechanisms of signaling and antagonistic effects of AT1 and AT2[J].Jpn Circ J.1997,61:807~813