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硬膜外吗啡等联合口服曲马多用于肛门手术后镇痛效果观察

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摘要 目的观察硬膜外吗啡等联合口服曲马多用于肛门手术后镇痛的疗效。方法 80例ASAⅠ~Ⅱ级在鞍麻下行痔瘘手术的患者随机分为A组和B组各40例。2组患者均于术毕前15 min^20 min硬膜外腔注入以生理盐水稀释的镇痛液5 mL:A组含吗啡0.5 mg+氯胺酮10 mg+地塞米松5 mg;B组含吗啡1 mg+氯胺酮10 mg+地塞米松5 mg。2组术后2 h开始口服曲马多缓释片100 mg/12 h,共4次。术后48 h内评价疼痛程度(VAS评分),记录不良反应发生率及患者满意度。结果术后48 h内各时点的VAS评分2组比较差异无统计学意义(P>0.05)。不良反应发生率A组明显低于B组,A组患者的满意度较高(P<0.05)。结论肛门手术后单次硬膜外微量吗啡等联合口服曲马多镇痛效果良好,不良反应发生率低,患者满意度高,且经济实用,宜于临床推广。
出处 《基层医学论坛》 2013年第13期1655-1656,共2页 The Medical Forum
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  • 1张银娣 钱曾年 等.医用基础药理学[M].南京:东南大学出版社,1994.274-277.
  • 2Vranken JH, van der Vegt MH, Kal JE, et al, Treatment of neuropathic cancer pain with continuous intrathecal administration of S +-ketamine [ J ] . Acta Anaesthesiol Scand,2004,48(2):249-252.
  • 3Bell RF, Eccleston C, Kalso E. Ketamine as adjuvant to opioids for cancer painaqualitative systematic review [ J ] . J Pain Symptom Manage,2004,28(2):100-102.
  • 4Bell R, Eccleston C, Kalso E.Ketamine as an adjuvant to opioids for cancer pain [ J ] .Cochrane Database Syst Rev,2003, (1):CD003351.
  • 5Kong PE, Snijdelaar DG, Crul BJ. Parenteral administration of low dose ketamine for the treatment of neuropathic pain in cancer patients [ J ] . Ned Tijdschr Geneeskd, 2002, 146(52):2556-2558.
  • 6Hurstvert O,Maurset A,Qye I. Interaction of the chiral forms of ketamine with opioid, phency clidine, and muscar in icreceptors [ J ]. Pharmacol Toxicol,1995, 77(4):355-359.
  • 7Fitzgibbon E J, Viola R.Parenteral ketamine as an analgesic adjuvant for severe pain: development and retrospective audit of a protocol for a palliative care unit [ J ] .J Palliat Med, 2005,8(1):49-57.
  • 8Yang CY, Wong CS, Chang JY, et al. Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain [ J ] . Can J Anaesth, 1996,43(4):379-383.
  • 9[1]The Italian Group for Antiemetic Research.Dexamethasone,Granisetron,or both for the prevention of nausea and vomiting during chemotherapy for cancer.New Eng J Med,1995,332:1-5.
  • 10[2]Fredrikson M,Hursti T,Fuest CJ et al.Nausea in cancer chemotherapy is inversely related to urinary cortisol excretion.Br J Cancer,1992,65:779-780.

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