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BCR-ABL酪氨酸激酶抑制剂研究进展 被引量:1

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摘要 BCR-ABL融合蛋白具有特殊的酪氨酸激酶活性,导致细胞异常。抑制酪氨酸激酶活性成为目前治疗Ph+白血病有效的方法之一。继首个以BCR-ABL融合基因为靶向的抗癌药物伊马替尼出现耐药以来,开发新的酪氨酸激酶抑制剂成为热门。本文就目前BCR-ABL酪氨酸激酶抑制剂的研究状况做一综述。
作者 吴莺
出处 《海峡药学》 2013年第5期5-8,共4页 Strait Pharmaceutical Journal
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