摘要
目的 :比较拉西地平和赖诺普利对高血压患者的疗效。方法 :6 0例高血压病 期或 期患者按服药情况分拉西地平组、赖诺普利组 ,治疗 8wk进行 2 4h动态血压监测。结果 :两药均能显著降压 ,降低偶测 BP的幅度无显著差异 ,拉西地平降低2 4h平均压和白天平均压的幅度大于赖诺普利。结论 :对轻中度高血压病拉西地平与赖诺普利是一种安全的药物 ,qd给药能维持 2 4h降压效应。
AIM: To compare the antihypertensive effects of lacidipine and losinopril in patients with essential hypertension. METHODS: Sixty patients with essential hypertension in stage Ⅰ and Ⅱ, divided into two groups, were treated with lacidipine or lisinopril respectively, their efficacy also was assessed by 24 hour ambulatory blood pressure monitoring. RESULTS: Both lacidipine and lisinopril significantly reduced systolic and diastolic blood prssures when compared with a placebo and no differences were obsverved between 2 drugs, lacidipine had greater reduction in 24 h mean and daytime mean ambulatory blood pressures than lisinopril. CONCLUSION: Lacidipine and lisinopril once daily are effective, safe and well tolerated in mild to moderate hypertensive patients.
出处
《中国临床药学杂志》
CAS
2000年第4期206-209,共4页
Chinese Journal of Clinical Pharmacy
