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不同人群2型糖尿病患者体脂含量百分比、体质指数与骨密度关系 被引量:6

A clinical research:Fat percent and BMI’s relationship with BMD in different groups of type 2 diabetic patients
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摘要 目的:探讨不同人群中2型糖尿病患者体脂含量百分比及体质指数与骨密度的关系。方法:对2型糖尿病259例患者测量身高、体重、腰围,用DEXA测量骨密度、体脂含量百分比,并检测生化指标。按不同肥胖评价标准进行分组,分析体脂含量百分比、体质指数与骨密度关系,并对影响骨密度因素作相关分析。结果:(1)按体质指数分组:肥胖组体脂含量百分比和体质指数高于超重组及正常组(P<0.05)。(2)按腰围分组:男肥胖组体脂含量百分比及骨密度高于男正常组(P<0.05);而女性肥胖组与女正常组骨密度比较差异无统计学意义(P>0.05);男肥胖骨密度高于女肥胖组(P<0.05)。(3)性别、体质指数、病程是影响骨密度的重要因素,男性的骨密度高于女性,体质指数和骨密度呈正相关,病程和骨密度呈负相关。结论:体脂含量百分比、BMI与骨密度有密切关系;老年2型糖尿病患者保持适当体重可能有利于预防骨质疏松症;老年2型糖尿病女性骨密度下降比老年男性明显。 Objective:To investigate fat percent and BMI's relationship with BMD in type 2 diabetic. Methods:A total of 259 subjects were involved in this study. Their height.weight and waist circumference (WC) were measured. BMD and fat percent were measured with dual energy X-ray absorptiometry (DEXA). They were divided according to different evaluation of obesity. Fat percent and BMI's relationship with BMD were analyzed. Results: (1)BMI-related obesity: The obesity group had a higher BMD and fat percent than other groups (P〈0.05); (2)WC-related obesity: The obesity group had a higher BMD and fat percent than normal in male (P〈0.05); In the female groups, there is no significant difference in BMD; Obesity in males had a higher BMD than in female; (3) Gender, BMI, and the duration of diabetes were important influencing factors of BMD. Male's BMD was higher than female's, BMI had a positive correlation with BMD, and the duration of diabetes showed a negative correlation with BMD.Conclusion:Fat percent and BMI had a close relationship with BMD; In the elderly T2DM, bone mass loss may be prevented if they keep proper weight. In elder T2DM,female's BMD declined more dramatically than male's.
出处 《交通医学》 2013年第2期166-169,共4页 Medical Journal of Communications
关键词 2型糖尿病 肥胖 体质指数 骨密度 骨质疏松症 obesity type 2 diabetes mellitus bone mineral density
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