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药物联合综合性心理干预治疗不稳定型心绞痛患者对照研究

A control study pharmacotherapy plus mental interventions in the treatment of unstable angina patients
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摘要 目的:探讨药物联合综合心理干预治疗不稳定型心绞痛患者的临床疗效。方法:将60例伴有不同程度焦虑抑郁情绪的不稳定型心绞痛患者随机分为两组,每组30例,两组均接受内科常规药物治疗,研究组患者联合综合心理干预治疗,观察6周。于治疗前及治疗6周末采用焦虑自评量表评定焦虑状况,抑郁自评量表评定抑郁状况,比较治疗后两组心血管事件发生情况。结果:治疗6周末,两组焦虑自评量表及抑郁自评量表评分均较治疗前有显著性下降(P<0.05或P<0.01),但研究组较对照组下降更显著(P<0.01);研究组心绞痛缓解及心电图ST段变化总有效率均显著高于对照组(x2=5.19、4.09,P<0.05),住院天数显著低于对照组(t=11.86,P<0.0.1)。结论:药物联合综合心理干预治疗能减轻或缓解不稳定型心绞痛患者的紧张、焦虑、抑郁情绪,改善躯体症状,减少心血管事件,缩短住院时间,提高临床疗效,显著优于单用药物治疗。 Objective: To explore the efficacy of mental intervention in patients with unstable angina pectoris based on pharmacotherapy. Methods:60 unstable angina patients with varying degrees of anxious emtions were randomly divided into research group (n = 30 ) receiving routine pharmacotherapy pills mental intervention and control group (n = 30 ) doing only routine pharmacotherapy for 6 weeks. Anxious status was assessed with the Self- rating Anxiety Scale(SAS) and depression status was assessed with the Self- rating Depression Scale(SDS) before treatment and at the end of 6th week treatment and developments of cadiovacular events were compared between the 2 groups after treatment. Results: At the end of 6th week treatment, SAS and SDS scores of both groups lowered more sig- nificantly compared with pre - treatment (P 〈 0.05 or 0.01 ) , those did more significantly of the research group than of the control group ( P 〈 O. O1 ) ; the total effective rate of angina pectoris and ECG ST segmen in research group were higher than the control group( x2 = 5. 19,4.09 ,P 〈 0.05 ) ;hospital days of research group were significantly lower than the control group( P 〈 0.01 ). Conclusions: Pharmacotherapy plus mental interventions can lessen or release anxiety and depression of negative emotions of patients with unstable angina pectoris, improve the somatic symptoms, reduce incidence of cardiovascular events, shorten length of stay, improve the clinical efficacy, is better than single pharmacotherapy.
出处 《中国民康医学》 2013年第9期13-14,86,共3页 Medical Journal of Chinese People’s Health
关键词 心绞痛 不稳定型 心理干预 心血管事件 Angina pectoris Unstable type Mental intervention Cadiovacular event
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