摘要
目的 :探索慢性乙肝重叠戊肝病毒感染后其临床表现、肝功能及对 HBV的影响。 方法 :对 30例慢性乙肝重叠戊型肝炎病毒感染后对临床表现、肝功能以及 HBV复制指标 (HBe Ag、HBV- DNA)与单纯乙肝和戊肝病人进行对比观察。 结果 :发现慢性乙肝重叠戊型肝炎病毒感染后其临床类型偏中、重型多 ,与单纯慢性乙肝、戊肝血清总胆红素、AL T、AST比较明显增高。与单纯乙肝比较 ,HBe Ag和 HBV- DNA阳性率显著降低 ,经检验有统计学差异。结论 :慢性乙肝重叠戊肝病毒感染是引起原有慢性乙肝病情加重的原因之一 ,并对
Objective: This study was to investigate the influence of HEV superinfection on chronic hepatitis B (CHB). Method: A clinical analysis was made befween CHB with HEV superinfection (30 cases) and simple CHB (30 cases) as wellas hepatitis E (HE) (34 cases), compared patient's clinical symptons, liver function and serum markers of HBV replication (HBeAg, HBV DNA). Results: It was discovered that the CHB with superinfection showed to have more moderate and severe cases than those of simple CHB and HE. The serum bilirubin, ALT and AST in CHB with HEV superinfection were significantly higher than those in CHB and HE. Additionaly, the positive rate of serum makers of HBV replication in CHB with HEV superinfection was remarkably decreased as comparing with simple CHB. Conclusion: We consider that HEV superinfection may be one of the aggravating factors toward CHB, and that HEV superinfection could inhibit the HBV replication.
出处
《新疆医科大学学报》
CAS
2000年第3期234-235,共2页
Journal of Xinjiang Medical University
