摘要
目的 了解血浆内皮素 (ET)与肺炎的发生、发展及疾病的轻重程度之间的关系。方法 用放射免疫法检测 73例肺炎患儿ET。结果 重症肺炎组的ET为 (112 6 1± 2 6 74)ng L ,较普通肺炎组〔 (6 6 71± 2 0 86 )ng L〕明显升高 (P <0 0 1) ;危重度评分在 70～ 90分组〔 (131 18± 2 7 33)ng L〕明显高于评分大于 90分组〔(73 95± 2 4 0 5 )ng L〕 (P <0 0 0 1)。结论 ET参与重症肺炎的发生与发展 ,与疾病轻重呈相关性 ,或许能为临床诊断、治疗和判断预后提供新的途径。
Objective To understand the relationship between the level of endothelia(ET)and the occurrence, development and the stages of pneumonia.Methods The level of ET was measured in 73 children with the pneumonia by radioimmunoassay.Results It was showed that the level of ET was significantly higher in children with serious diseases〔(112 61±26 74)mg/L〕than that in children with general pneumonia〔(66 71±20 86)ng/L,P<0 001)〕.According to the critical care scores, the level of ET was higher in children at 70～90 scores groups〔(131 18±27 33)ng/L〕than that at more than 90 scores group〔(73 95±24 05)ng/L〕(P<0 001).Conclusion These results suggest that ET is involved in the occurrence and development of pneumonia, and is related with the stages of pneumonia.Levels of ET should be a new parameter on diagnosing, treatment and judging prognosis of the pneumonia.
出处
《中国全科医学》
CAS
CSCD
2000年第4期272-273,共2页
Chinese General Practice
