期刊文献+

开腹手术后切口局部持续浸润麻醉疗效的随机对照研究 被引量:13

The effect of continuous local anesthetic infiltration after laporotomy: a randomized controlled to study
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摘要 目的使用前瞻性随机对照方法研究开腹手术后使用切口镇痛泵持续切口浸润麻醉的镇痛疗效和副反应。方法收集2011年5月至2012年5月间在我院普外科接受经右侧肋缘下切口进行开腹手术的30例患者(手术由同一组医生完成),随机分成两组:对照组(生理盐水持续切口浸润,n=15)和切口镇痛泵组(罗哌卡因持续切口浸润麻醉,n=15),所有患者同时使用舒芬太尼静脉麻醉自控泵,分别记录术后疼痛评分、累计舒芬太尼使用量、恶心呕吐发生、术后镇静评分、肠道功能恢复时间、住院时间、有无切口感染等。结果使用切口镇痛泵进行术后切口局部持续浸润麻醉无明显副作用。与对照组相比,使用切口镇痛泵组具有更好的术后镇痛效果(P<0.05),更少的舒芬太尼使用量(P<0.05),更短的肠道功能恢复时间(P<0.05)和平均住院时间(P<0.05)。结论使用切口镇痛泵进行切口持续浸润麻醉是一种安全有效的术后止痛方法,可以加速患者术后恢复,减少住院时间。 Objective To assess the analgesic effect and side effect of continuous local anesthetic infiltrationafter laparotomy in this randomized controlled study. Methods From May 2011 to May 2012, thirty cases of laparotomy by right subcostal incision were randomly divided into two groups: control group (continuous local anesthetic infiltration by normal saline, n=15) and incision analgesia pump group (continuous local anesthetic infiltration by ropivacaine, n=15). All patients from both groups used sufentanil intravenous anesthesia controlled pump simutaneously. Postoperative pain score, accumulative usage volume of sufentanil, postoperative nausea and vomiting, sedation score, intestinal function recovery time, hospitalization time and incision infection were recorded. Results There was no obvious side effect on pain controlling by continuous local ropivacaine infiltra- tion using incision analgesia pump. Compared with the control group, the incision analgesia pump group had significantly better postoperative pain control (P〈0.05), less accumulative usage volume of sufentanil (P〈0.05), shorter recovery time of the bowel function (P〈0.05) and mean hospitalization time (P〈0.05). Conclusion The continuous local ropivacaine infiltration using incision analgesia pump is a safe and effective method for postop- erative pain relief. It could accelerate postoperative recovery and reduce hospitalization time.
出处 《肝胆胰外科杂志》 CAS 2013年第3期207-209,共3页 Journal of Hepatopancreatobiliary Surgery
关键词 局部麻醉 罗哌卡因 切口浸润 术后镇痛 local anesthesia ropivacaine incision infiltration postoperative analgesia
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参考文献10

  • 1Bray DA, Jr Nguyen J, Craig J, et al. Efficacy of a localanesthetic pain pump inabdominoplasty [J]. Plast ReconstrSurg, 2007, 119(3): 1054-1059.
  • 2Payabvash S, Beheshtian A, Salmasi AH, et al. Chronic mor-phine treatment induces oxidant and apoptotic damage in themice liver [J], Life Sci, 2006,79(10): 972-980.
  • 3Zhou B, Wang J, Yan Z, et al. Liver cancer: effects, safety,and cost-effectiveness of controlled-release oxycodone forpain control after TACE [J]. Radiology, 2012, 262(3): 1014-1021.
  • 4White PF. The changing role of non-opioid analgesic tech-niques in the management of postoperative pain [J]. AnesthAnalg, 2005, lOl(Suppl): S5-22.
  • 5Meechan JG. Pain control in local analgesia [J], Eur ArchPaediatr Dent, 2009, 10(2): 71-76.
  • 6Anastasiou J, Karatzas T,Felekouras E,et al. Radical nephre-ctomy with transperitoneal subcostal incision for large andlocally advanced tumors of the right kidney [J]. AnticancerRes, 2012,32(11): 5023-5029.
  • 7刘付丽,唐红丽,董晓西,施克俭,郑浩,徐旭仲.帕瑞昔布联合腹腔内罗哌卡因用于腹腔镜胆囊切除术后镇痛[J].肝胆胰外科杂志,2011,23(1):21-23. 被引量:8
  • 8Binning AR, Przesmycki K, Sowinski P’ et al. A randomisedcontrolled trial on the efficacy and side-effect profile (nausea/vomiting/sedation) of morphine-6-glucuronide versus mor-phine for post-operative pain relief after major abdominalsurgery [J]. Eur J Pain, 2011, 15(4): 402-408.
  • 9Fredman B, Shapiro A, Zohar H, et al. The analgesic efficacyof patient-controlled ropivacaine instillation after Cesareandelivery [J]. Anesth Analg, 2000, 91(6): 1436-1440.
  • 10Lluis F, Romero Simo M, Marquez Peiro JF, et al. Safety of amultiperforated catheter implanted in the surgical wound forthe continuous infusion of local anaesthetics in post-opera-tive analgesia [J]. Cir Esp, 2011,89(9): 613-617.

二级参考文献11

  • 1Kahokehr A,Sammour T,Soop M,et al.Intraperitoneal use of local anesthetic in laparoscopic cholecystectomy:systematic review and metaanalysis of randomized controlled trials[J].Hepatobiliary Pancreat Sci,2010,17(5):637-656.
  • 2Bnddy AP,Mehta S,Rhodes M.The effect of intraperitoneal local anesthesia in laparoscopic cholecystectomy:a systematic review and meta-analysis[J].Anesth Analg,2006,103(3):682-688.
  • 3Wills VL,Hunt DR.Pain after laparoscopic cholecystectomy[J].Br J Surg,2000,87(3):273-84.
  • 4Gupta A,Thorn SE.Axelsson K,et al.Postoperative pain relief using intermit tent injections of 0.5% ropivacaine through a cat heter after laparoscopic cholecystectomy[J].Anesth Analg,2002,95(2):450-456.
  • 5Luscombe KS,McDonnell NJ,Muchatuta NA,et al.A randomised comparision of parecoxib versus placebo for pain management following minor day stay gynaecological surgery[J].Anaesth Intensive Care,2010,38(1):141-148.
  • 6Langford RM,Joshi GP,Gan TJ,et al.Reduction in opioidrelated adverse events and improvement in function with parecoxib followed by valdecoxib treatment after non-cardiac surgery:a randomized,double-blind,placebo-controlled,parallel-group trial[J].Clin Drug Investig,2009,29(9):577-590.
  • 7Paech MJ,llett KF,Hackett LP,et al.Disposition and clinical outcome after intraperitoneal meperidine and ropivaeaine administration during laparoscopic surgery[J].Anesth Analg,2008.106(1):278-286.
  • 8Pasqualucci A,de Angelis V,Contardo R,et al.Preemptive analgesia:intraperitoneal local anesthetic in laparoscopic cholecystectomy,a randomized,double-blind,placebo-controlled study[J].Anesthesiology,1996,85(1):11-20.
  • 9Karaaslan D,Sivaci R G,Akbulut G,et al.Preemptive analgesia in laparoscopic cholecystectomy:a randomized controlled study[J].Pain Pract,2006,6(4):237-241.
  • 10Bisgaard T.Analgesic treatment after laparoscopic cholecystectomy:a critical assessment of the evidence[J].Anesthesiology,2006,104(4):835-846.

共引文献7

同被引文献90

  • 1杨春梅.持续静脉自控镇痛在肝胆手术的临床观察和护理[J].今日健康,2016,15(5):290-290. 被引量:2
  • 2李秀泽,谭玲.罗哌卡因的研究近况及临床应用[J].实用医药杂志,2004,21(6):554-555. 被引量:10
  • 3陈新忠,王保国,温琳琳,张建伟,郑巍.0.5%罗哌卡因切口浸润麻醉对全麻开颅术中血流动力学及血糖的影响[J].中国医师进修杂志,2007,30(3):8-10. 被引量:7
  • 4秦明峰.瑞芬太尼与吗啡及芬太尼用于老年患者术后自控镇痛的效果比效[J].新乡医学院学报,2007,24(4):380-382. 被引量:18
  • 5LIU SS, RICHMAN JM, TH1RLBY RC, et al. Efficacy of con- tinuous wound catheters delivering local anesthetic for postopera-rive analgesia: a quantitative and qualitative systematic review of randomized controlled trials[J]. J Am Coil Surg, 2006, 203(6): 914-932.
  • 6LASTYPACIK TP. Pain management in augmentation mammap: a randomized, comparative study of the use of a continuous infu- sion versus self-administration intermittent bolus of a local anes- thetic[J]. Aesthetic Surg J, 2004, 24(6): 523-530.
  • 7TIMOTHY GC, JOHN RC, CHRISTOPHER H, et al. Plasma ropivacainc levels following scalp block for awake craniotomy[J]. J Neurosurg Anesthesiol, 2004, 16(2): 147-150.
  • 8HINNERK W, HAGEN B, ILKA V, et al. clini:al usefulness, saety, and plasma concentration of ropivaeaine 0.5% for inguinal hernia repair in regional anesthesia[J]. Reg Anesth Pain Med, 2001, 26: 348-351.
  • 9UDELSMANN A, SILVA WA, DE MORAES AC, et al. Homo- dynamic effects of ropivacaine and lcvobupivacaine intravenous injection in swines[J]. Acta Cir Bras, 2009, 24(4): 296-302.
  • 10FREDMAN B, SHAPIRO A, ZOHAR E, et al. The analgesic ef- ficaey of patient-controlled ropivacaine instillation after Cesza'ean delivery[J]. Anesth Analg, 2000, 91(6): 1436-1440.

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