摘要
目的:探讨宫颈上皮内瘤变(CIN)Ⅰ-Ⅱ级患者用聚焦超声治疗后的妊娠及其结局。方法:回顾性分析2005年1月至2007年6月因CINⅠ-Ⅱ行聚焦超声治疗的254例后分娩患者的妊娠时间、妊娠结局和终止妊娠方式。结果:254例患者,年龄20-36岁,平均(27.36±2.26)岁。254例妊娠患者中,3例异位妊娠,8例流产,243例分娩。在已分娩的243例患者中,3例早产,早产发生率为1.23%(3/243);18例胎膜早破,胎膜早破发生率为7.41%(18/243);无足月低体重儿发生;65例顺产,2例产钳助产,155例行剖宫产术,剖宫产率为63.98%(155/243)。剖宫产率较同期产科剖宫产率有显著统计学差异(χ2=14.7621,P<0.01)。分析剖宫产原因,其中因社会因素而选择剖宫产的高达30例,去除该因素后,剖宫产率为51.44%,与同期剖宫产率51.32%相比无差异(χ2=0.001 37,P>0.05)。结论:宫颈聚焦超声是治疗宫颈上皮内瘤变Ⅰ-Ⅱ安全有效的方法,对患者的妊娠及其结局无明显影响,不增加早产和低出生体重儿发生率。
Objective： To investigate the effects of focused ultrasonic therapy on pregnancy outcomes of patients with cervical intraepithelial neoplasia Ⅰ-Ⅱ.Methods： The pregnancy time,pregnancy outcome and termination of pregnancy way of 254 pregnancy women who had focused ultrasonic therapy with cervical intraepithelial neoplasiaⅠ-Ⅱ from January 2005 to June 2007 were retrospectively collected and analyzed. Results： The average age of 254 patients were（27.36 ± 2.26） years old（range 20-36 years old）.Of 254 pregnancy cases,there were 3 cases of ectopic pregnancy,8 cases of abortion and 243 childbirths. In 243 childbirth patients,incidence of premature birth and premature rupture of membranes was 1.23%（3/243） and 7.41%（18/243） respectively,and no full-term low birth weight children occurred.Of 65 natural delivery cases,2 cases were forceps delivery;155 cases adopted routine cesarean,the cesarean rate was 63.98%（155/243）,which was significant higher than the obstetric cesarean section rate in the same period（P 0.01）.However,after removing the social factors for cesarean selection,the cesarean rate showed no significant difference from the obstetric cesarean section rate in the same period（51.44% vs 51.32%,P 0.05）.Conclusion： Focused ultrasound is a safe and effective treatment for patients with CIN Ⅰ-Ⅱ,it has no significant impact on the patient’s pregnancy and delivery outcomes,and will not increase the incidence of premature birth and low birth weight infants.
出处
《武汉大学学报（医学版）》
CAS
北大核心
2013年第3期457-459,共3页
Medical Journal of Wuhan University
关键词
宫颈上皮内瘤变Ⅰ-Ⅱ级
聚焦超声
妊娠结局
Cervical Intraepithelial NeoplasiaⅠ-Ⅱ
Focused Ultrasonic Therapy
Pregnancy and Delivery Outcome
