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左氧氟沙星替代三联阿莫西林治疗幽门螺杆菌阳性胃溃疡临床疗效观察 被引量:2

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摘要 目的探究并分析左氧氟沙星替代三联阿莫西林治疗幽门螺杆菌(hp)阳性胃溃疡的临床疗效。方法选取该院自2008年5月—2010年5月收治的幽门螺杆菌感染引起的胃溃疡患者100例,将其作为临床研究对象。随机分为A、B两组,两组患者均为50例,A组采用左氧氟沙星的三联疗法,即为观察组;B组患者采用阿莫西林三联疗法治疗,即对照组。1周后,观察比较两组患者的治疗效果(溃疡治愈率和不良反应发生率)。结果 A组患者的治疗效果优于B组。差异有统计学意义(P<0.05)。结论含左氧氟沙星的三联疗法替代阿莫西林的三联疗法对幽门螺杆菌引起的胃溃有着很好的疗效,并且不良反应率低。值得在临床广泛推广。
作者 祁玉龙
出处 《中外医疗》 2013年第10期110-110,112,共2页 China & Foreign Medical Treatment
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  • 1张信,周和,孙宏慧,区都,田伟.雷贝拉唑与奥美拉唑三联疗法治疗幽门螺杆菌阳性消化性溃疡疗效比较——附40例分析[J].新医学,2004,35(7):401-403. 被引量:46
  • 2无,许国铭(整理),邹多武(整理).中国消化性溃疡治疗现状调查报告[J].中华消化杂志,2007,27(2):114-117. 被引量:116
  • 3Konturek SJ. Konlurek PC, Konturek JW, et al. Helicobacter pylori and its involvement in gastritis and peptic ulcer formation.J PhysiolPharmacol, 2006,57 (Suppl 3): 29-50.
  • 4Atherton JC. The pathugenesis of Helicobacter pylori induced gastro duodenal diseases. Annu Rev Pathol,2006,1:63-96.
  • 5Hamajima N. Persistent Helieobacter pylori infection and genetic polymorphisms of the host. Nagoya J Med Sci, 2003, 66: 103-117.
  • 6Dincer D, Duman A, Dikici H, et al. NSAID-related upper gastrointestinal bleeding: are risk factors considered during prophylaxis? Int J Clin Pract,2006,60 : 546-548.
  • 7Zapata Colindres JC, Zepeda Gomez S, Montano Loza A, et al. The association of Helicobacter pylori infection and nonsteroidal anti inflammatory drugs in peptic ulcer disease. Can J Gastroenterol, 2006, 20: 277-280.
  • 8Metz DC, Sostek MB, Ruszniewski P, et al. Effects of esomeprazole on acid output in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion. Am J Gastroenterol, 2007, 102:2648-2654.
  • 9Egan BJ, Katicic M, O'Connor HJ, et al. Treatment of Helicobacter pylori. Helicobacter, 2007, 12:31-37.
  • 10Zullo A, Rinaldi V, Winn S, et al. A new highly effective short-term therapy schedule for Helicobacter pylori eradication. Aliment Pharmacol Ther, 2000. 14: 715-718.

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  • 1束庆文,周娜,蔡善武,疏东升,刘太平,汪全红,徐正富.比较左氧氟沙星与阿莫西林在三联疗法中根除幽门螺杆菌的作用[J].安徽医学,2007,28(4):308-311. 被引量:11
  • 2Chey WD, Wong BC. American College of Gastro- enterology guideline on the management of Helico- bacter pylori infection. Am ] Gastroenterol 2007; 102: 1808-1825 [PMID: 17608775].
  • 3Chen MC, Lei WY, Lin JS, Yi CH, Wu DC, Hu CT. Levofloxacin-amoxicillin/clavulanate-rabeprazole versus a standard seven-day triple therapy for eradication of Helicobacter pylori infection. Biomed Res Int 2014; 2014:158520 [PMID: 24995271 DOI: 10.1155/2014/158520].
  • 4Meyer JM, Silliman NP, Wang W, Siepman NY, Sugg JE, Morris D, Zhang J, Bhattacharyya H, King EC, Hopkins RJ. Risk factors for Helicobacter pylori resistance in the United States: the surveillance of H. pylori antimicrobial resistance partnership (SHARP) study, 1993-1999. Ann Intern Med 2002; 136:13-24 [PMID: 11777360].
  • 5Gisbert JP, Bermejo F, Castro-FernKndez M, Porez- Aisa A, Fernandez-Bermejo M, Tomas A, Barrio J, Bory F, Almela P, Sanchez-Pobre P, Cosme A, Ortiz V, Nino P, Khorrami S, Benito LM, Carneros JA, Lamas E, Modolell I, Franco A, Ortuao J, Rodrigo L, Garcia-DurKn F, O'Callaghan E, Ponce J, Valer MP, Calvet X. Second-line rescue therapy with levo- floxacin after H. pylori treatment failure: a Spanish multicenter study of 300 patients. Am J Gastroenterol 2008; 103:71-76 [PMID: 17764498].
  • 6Kanizaj TF, Kunac N. Helicobacter pylori: future perspectives in therapy reflecting three decades of experience. World J Gastroenterol 2014; 20:699-705 [PMID: 24574743 DOh 10.3748/wjg.v20.13.699].
  • 7Higgins JPT, GreenS, editors. Cochrane Handbook for systematic reviews of interventions version 5.1.0 ]updated March 2011]. The Cochrane collabora- tion, 2011 Available from: http://www.cochrane- handbook.org.
  • 8Smith SM, Haider RB, O'Connor H, McNamara D, O'Morain C. Practical treatment of Helicobacter py- lori: a balanced view in changing times. Eur ] Gas- troenterol Hepatol 2014; 26:819-825 [PMID: 24892516 DOI: 10.1097/MEG.0000000000000130].
  • 9Wu TS, Hu HM, Kuo FC, Kuo CH. Eradication of Helicobacter pylori infection. Kaohsiung J Med Sci 2014; 30:167-172 [PMID: 24656156 DOI: 10.1016/ j.kjms.2013.11.003].
  • 10Schrauwen RW, Janssen MJ, de Boer WA. Seven- day PPI-triple therapy with levofloxacin is very effective for Helicobacter pylori eradication. Neth J Med 2009; 67:96-101 [PMID: 19307680].

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