期刊文献+

新生儿脐带血乙肝两对半模式的比较

Comparing Neonatal Cord Blood Two Pairs of Semi-hepatitis B Mode
暂未订购
导出
摘要 目的对乙肝表面为阳性抗原的母亲所产下的婴儿,采集其脐带血,并对其乙肝两对半进行检查,通过对新生儿感染乙肝的情况以及乙肝两对半所具有的模式的观察,来对母婴之间乙肝的垂直传播进行有效控制,以降低感染乙肝概率。方法对标本进行离心,并将血清分离出来,采用酶联免疫的吸附试验,对乙肝两对半进行检查。结果脐带血616例新生儿乙肝两对半有352例为阴性乙肝两对半,为总数的57.14%,264例新生儿能够检测出至少1项为阳性,为总数的42.86%,选取同期对血清标本的乙肝两对半进行检测的2786例新生儿,将该研究中的乙肝两对半具体模式列表之后进行对比和匹配,采用χ2检验,结果显示P<0.01,差异有统计学意义。结论新生儿脐带血以及临床中血清标本当中各自的乙肝两对半模式存在着显著差别。大大降低了新生儿的乙肝感染概率。 Objective To the hepatitis B surface antigen positive mothers gave birth to the baby, collecting the umbilical cord blood and the two pairs of semi-hepatitis B are examined. Throughthe newborn hepatitis B infection and two pairs of semi-hepatitis B with patterns observed, to mother-to-child vertical transmission of hepatitis B control effectively, in order to reduce hepatitis B infection probability. Methods Specimens were centrifuged and the serum is separated, using enzyme immunoassay adsorption test on two pairs of semi-hepatitis B check. Results 616 cases of neonatal umbilical cord blood of two pairs of semi-hepatitis.B 352 cases negative for two pairs of semi-hepatitis B, 57.14% of the total, 264 cases of neonatal can detect at least a positive, for 42.86% of the total, chosen at the serum samples of two pairs of semi-hepatitis B were detected in 2786 cases of newborn infants.This study in hepatitis B two on the list of specific mode after comparison and matching using χ^2 test, results showed that P〈0.01, therefore, there is a statistically significant difference between. Conclusion The neonatal umbilical cord blood as well as clinical serum samples of the respective two pairs of semi-hepatitis B model exist significant difference. It greatly reducing the neonatal hepatitis B infection probability.
作者 何芸
出处 《中外医疗》 2013年第10期8-10,共3页 China & Foreign Medical Treatment
关键词 新生儿 脐带血 乙肝两对半模式 Neonates Cord Blood Ttwo Pairs of Semi-hepatitis B Mode
  • 相关文献

参考文献8

二级参考文献33

  • 1王吉耀,刘维田,胡美玉,朱无难,童家琪.甘草酸(强力宁)对成纤维细胞Ⅰ、Ⅲ型前胶原mRNA表达的抑制作用[J].肝脏,1996,1(2):81-83. 被引量:49
  • 2杨超美,陈丹林,励世芳,马凤鸣,陈益,白红,向真,王宏禧,宋珍珠,胡宗汉.乙肝基因工程疫苗阻断HBV母婴传播的效果观察[J].中华流行病学杂志,1994,15(6):343-345. 被引量:14
  • 3张定凤.中华医学会第三次全国传染病与寄生虫病学术会议纪要[J].中华内科杂志,1989,28(4):196-198. 被引量:1
  • 4陈奇.中药药理研究方法学[M].北京:人民卫生出版社,1994.362、757.
  • 5胡亚美 江载芳.实用儿科学第7版[M].北京:人民卫生出版社,2002,12.775.
  • 6沙庆洪 梁瑞林.乙型肝炎病毒母婴传播的研究[J].中华预防医学杂志,1986,20(5):264-264.
  • 7William Flarman,Alessandro R zanetti,Peter Karayiamis,et al.1990 Vaccine-induced Secape Mutant of Hepatitis Bvirus[J].The Lancet I:325-330.
  • 8Bertoletti A, Maini MK. Protection or damage: a dual role for the virusspecific cytotoxic T lymphocyte response in hepatitis B and C infection? Curr Opin Microbiol, 2000, 3(4): 387-392.
  • 9Ebert LM, McColl SR. Up-regulation of CCR5 and CCR6 on distinct subpopulations of antigen-activated CD4+ T lymphocytes. J Immunol, 2002, 168(1): 65-72.
  • 10Ando K, Guidotti LG, Wirth S, et al. Class Ⅰ-restricted cytotoxic T lymphocytes are directlycytopathic for their target cells in vivo. J Immunol, 1994, 152(7): 3245-3253.

共引文献58

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部