摘要
目的探讨全髋关节置换术后低分子肝素对深静脉血栓的预防效果,比较溶血栓和抗凝治疗对血栓的治疗效果。方法实验组86例全髋关节置换术施以低分子肝素钠腹壁皮下注射,预防下肢深静脉血栓的形成,对照组78例全髋关节置换术后发现血栓才给以尿激酶和肝素钠、华法林处理。结果实验组和对照组在术中、术后的出血量和输血量无显著差异,无统计学意义(P>0.05);实验组术后出现下肢深静脉血栓形成者仅为3例,对照组为14例,两组差异具有统计学意义(P<0.05)。结论全髋关节置换术后使用低分子肝素进行抗凝,可以显著降低下肢深静脉血栓的发生率,具有良好的安全性。
Objective Study the prophylaxis effect of low molecular weight heparin on deep venous thrombosis after total hip arthroplasty, and compare the curative effect of thrombolytic and anticoagulant therapy for thrombosis. Methods 86 cases of the experimental group were given abdominal subcutaneous injection with low molecular weight hparin for prevention of lower limb deep venous thrombsis; 78 patients of the control group were treated with urokinase, heparin sodium and warfarin after the thrombi were observed. Results There was no significant difference between the two groups in terms of intraoperative blood loss, postoperative blood loss, and blood transfusion volume （P 〉0.05）. After the surgery, 3 cases of deep vein thrombosis were discovered in the experimental group while there were 14 cases in the control group. The difference between the two groups was significant （ P 〈 0.05 ）. Conclusion Using low molecular weight heparin for anticoagulation after total hip replacement surgery could significantly reduce the incidence of deep vein thrombosis with good safety.
出处
《局解手术学杂志》
2013年第3期285-287,共3页
Journal of Regional Anatomy and Operative Surgery
关键词
全髋关节置换
深静脉血栓
低分子肝素
抗凝
total hip replacement
deep venous thrombosis
low molecular weght heparin
anticoagulation
