摘要
目的 了解老年人良性前列腺增生（BPH）及代谢综合征（MS）的患病率,探讨老年人BPH合并MS患者的高危代谢因素. 方法 选取2010年1-12月在我院体检中心查体的老年男性490例,分为BPH合并MS组246例,单纯MS组55例,单纯BPH组44例,对照组为无BPH且无MS组145例.测量身高、体质量,计算体质指数（BMI）；测量收缩压、舒张压,检测空腹血糖（FBG）、血总胆固醇（TC）、三酰甘油（TG）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、谷内转氨酶（ALT）、血肌酐、糖化血红蛋白（HbA1c）、血尿酸等指标. 结果 BPH及MS患病率随增龄而增加（x2=810.71、732.18,均P＜0.05）,BPH合并MS老年人年龄、BMI、血压、FBG、TG、TC、LDL-C、血尿酸、HbA1c显著高于对照组老年人,HDL-C低于对照组老年人（均P＜0.05）；BPH合并MS的老年人年龄明显高于单纯MS的老年人（P＜0.05）；BPH合并MS的老年人年龄、BMI、血压、FBG、TG明显高于单纯BPH老年人,HDL-C低于单纯BPH老年人（均P＜0.05）.多因素Logistic回归分析显示,年龄70岁以上、肥胖、高血压、高FBG、高TG、低HDL-C是BPH合并MS的独立危险因素（OR值分别为2.947、4.470、4.790、11.589、27.850、0.391,均P＜0.05）. 结论 BPH及MS患病率随增龄而增加,年龄70岁以上、肥胖、高血压、高FBG、高TG及低HDL-C是BPH合并MS发病的危险因素.
Objective To investigate the prevalences of benign prostatic hyperplasia （BPH） and metabolic syndrome （MS） and to analyze the risk factors for benign prostatic hyperplasia and metabolic syndrome in the elderly.Methods A total of 490 elderly men undergoing health examination in our hospital from January 2010 to December 2010 were divided into BPH and MS group （n=246）,MS group （n=55）,BPH group （n=44）,non-BPHandnon-MSgroup （control,n =145）.Body height,body weight,body mass index （BMI）,systolic blood pressure （SBP）,diastolic blood pressure （DBP） were detected.Fasting blood glucose （FBG）,serum total cholesterol （TC）,triglyceride （TG）,low-density lipoprotein cholesterol （LDL-C）,high-density lipoprotein cholesterol （HDL-C）,alanine a minotransferase （ALT）,creatinine （CRE）,glycated hemoglobin （HbA1c）,serum uric acid （UA） and other indicators were measured.Results The prevalences of BPH and MS were increased with age （x 2=810.71,732.18,both P〈0.05）.Age,BMI,blood pressure,the levels of FBG,TG,TC,LDL-C,UA and HbA1c were significantly higher in BPH and MS group than in control group （all P〈0.05）,while HDL-C concentration was significantly lower in group BPH and MS than in control group （P〈0.05）.Age was significantly higher in group BPH and MS than in MS group （P〈0.05）.Age,BMI,blood pressure,levels of FBG and TG were significantly higher in group BPH and MS than in BPH group （all P〈0.05）,while HDL-C concentration was significantly lower in group BPH and MS than in group C （P〈0.05）.Multivariate logistic regression analysis showed that age〉70 years,obesity,hypertension,high FBG,high TG,lower HDL-C were independent risk factors for BPH and MS （OR：2.947,4.470,4.790,11.589,27.850,0.391,respectively,all P〈 0.05）.Conclusions The prevalences of BPH and MS are gradually increased with ageing in elderly men.Age 〉 70 years,obesity,hypertension,high fasting glucose,hypertriglyceridemia and lower HDL-C are the risk factors for BPH and MS.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2013年第5期496-499,共4页
Chinese Journal of Geriatrics
关键词
前列腺增生
代谢综合征X
危险因素
Prostatic hyperplasia
Metabolic syndrome X
Risk factors
