摘要
用两步法合成了3种不对称二亚胺L,LMe和LCl。起始原料席夫碱2-羟基-N-(5-硝基糠叉)苯胺(SB-NO2)用5-硝基糠醛和2-羟基苯胺反应制得。SB-NO2然后在溶液中被还原为其氨基衍生物SB-NH2。在SB-NH2溶液中分别加入2-羟基苯甲醛,2-羟基-5-甲基苯甲醛和2-羟基-5-氯苯甲醛制得二亚胺化合物L,LMeand LCl。同时还合成了这些配体的Fe(Ⅲ)and Ni(Ⅱ)的二聚和双核配合物。用元素分析、LC-MS、IR、UV-Vis、1H and13C-NMR、TGA、电导率和磁性测量等对二亚胺及其配合物进行了表征,还研究了席夫碱配体及其配合物对5种细菌的抗菌活性。所有化合物对大肠埃布氏菌、枯草芽孢杆菌、小肠结肠炎耶尔森氏菌均有中等强度的活性。Fe(Ⅲ)配合物对绿脓假单胞菌(绿脓杆菌)具有最高活性。
Three new unsymmetric diimines L, L_Me, and L_Cl were synthesized by a two-step process. Initially, the starting Sehiff base 2-hydroxy-N-（5-nitrofurylidene）aniline （SB-NO2） was obtained by using 5-nitro-furfural and 2- hydroxyaniline. Nitro group of SB-NO/was reduced into its amino derivative, SB-NH2, in solution. Diimines L, L_Me and L_Cl were obtained with the addition of 2-hydroxybenzaldehyde, 2-hydroxy-5-methylbenzaldehyde and 2- hydroxy-5-chlorobenzaldehyde, respectively, into SB-NH2 solution. Dimeric, binuclear Fe（Ⅲ） and Ni（Ⅱ） complexes of these ligands were also synthesized. Diimines and their complexes were characterized by elemental analyses, LC-MS, IR, electronic spectra, ^1H and ^13C-NMR spectra, TGA, conductivity and magnetic measurements. The antibacterial activities of the ligands and the complexes were investigated against five bacteria. All of the compounds showed moderate activities against Escherichia coli, Bacillus subtilis and Yersinia enterecolitica. The highest activity values were obtained by Fe（Ⅲ）） complexes against Pseudomonas aeruginosa.
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
2013年第6期1227-1234,共8页
Chinese Journal of Inorganic Chemistry
基金
Gazi Universtiy Research foundations资助项目,(FEF 05/2003-64)and(FEF 05/2005-37)~~
