摘要
目的:探讨冬虫夏草(CS)提取液对大鼠比目鱼肌肌梭传入放电的影响。方法:雌性SD大鼠20只,麻醉后行气管插管术和颈外静脉插管术,在比目鱼肌神经上分离神经细束,记录肌梭的传入放电,观察CS对放电的影响。结果:分别注射50 mg.kg-1、100 mg.kg-1、150 mg.kg-1CS提取液后,肌梭传入放电峰值频率均明显增加,且随着药物浓度升高,放电频率明显增加,放电持续时间明显延长。结论:CS提取液明显增加大鼠肌梭的传入放电频率,且与剂量呈依赖关系。
Objective To observe the effect of cordyceps extracting solution （CS） on the afferent discharge frequency of rats muscle spindle. Methods The endotracheal intubation and the external jugular vein intubation under anaesthesia were performed for 20 female SD rats, then the nerve filaments of soleus muscle were isolated in vivo to observe the influence from the CS on muscle spindle afferents. Results After administration of 50 mg. kg-1 of soleus muscle spindle in rats increased ,100 mg-1 kg-1, and 150 mg. kg-1 CS, the spontaneous discharge signifi dose-dependent. Conclusion CS can effectively rats. cantly. The effect of CS on muscle spindle afferents was increase afferent discharge of soleus muscle spindle of
出处
《中国运动医学杂志》
CAS
CSCD
北大核心
2013年第4期333-336,共4页
Chinese Journal of Sports Medicine
基金
国家自然科学基金资助项目(30901583)
教育部新世纪优秀人才支持计划项目(NCET-10-0680)
陕西省科学技术研究发展计划项目(2009KW-20)
中央高校基本科研业务费专项资金资助项目(xjj20100181)
关键词
肌梭
传入放电
冬虫夏草
muscle spindle, afferent discharge, cordyceps
