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连续肾脏替代治疗患者抗菌药物剂量调整临床药师干预效果的回顾性分析 被引量：7

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摘要 目的评估重症监护室(ICU)临床药师在连续肾脏替代治疗(CRRT)患者抗菌药物剂量调整中的作用与价值。方法对本院综合重症监护室行连续肾脏替代治疗患者抗菌药物使用进行常规药学监护,对用药剂量进行评估和干预,并提取相关数据进行统计和分析。结果研究期间临床药师总共提出药学建议220例次,其中77.27%为临床药师主动提出的,83.18%可被临床医生完全采纳。肾衰竭连续连续肾脏替代治疗治疗、肾衰竭间断连续肾脏替代治疗治疗、肾功能正常连续肾脏替代治疗治疗是药学建议中最常见的3种类型,药学建议数量分别为78(35.45%)、105(47.73%)、21(9.55%)。分三阶段对药学建议分析显示,阶段II每例患者平均药学建议数显著低于阶段I(P<0.05),阶段III与阶段II则基本接近(P>0.05)。结论临床药师可为危重病连续肾脏替代治疗患者提供合理化的抗菌药物剂量调整建议,是重症监护室临床药师参与治疗团队的一个很好切入点。
作者 姜赛平 朱正怡 肖永红 卢晓阳
机构地区 浙江大学医学院附属第一医院 浙江大学医学院附属儿童医院
出处 《中国药学杂志》 CAS CSCD 北大核心 2013年第10期827-830,共4页 Chinese Pharmaceutical Journal
关键词 重症监护室 连续肾脏替代治疗 抗菌药物 剂量调整 药学监护
分类号 R969.3 [医药卫生—药理学]
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参考文献15

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二级参考文献35

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共引文献13

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二级引证文献42

中国药学杂志
2013年 第10期

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