摘要
目的探讨慢性萎缩性胃炎胃镜下不同病理改变与幽门螺杆菌感染的关系,为临床诊治提供借鉴。方法对8012例行胃镜检查后诊断为慢性萎缩性胃炎患者的胃镜形态表现与幽门螺杆菌感染及病理结果进行回顾性分析。结果胃镜下诊断为慢性萎缩性胃炎共1121例,其中A组(单纯萎缩性胃炎)共532例,B组(萎缩性胃炎伴增生)共589例;A组患者病理诊断为萎缩性胃炎385例,诊断符合率为72.37%;B组患者病理诊断为萎缩性胃炎505例,诊断符合率为85.74%,两组差异有统计学意义(P<0.05);A组患者病理结果肠上皮化生54例,不典型增生56例;B组患者病理结果肠上皮化生94例,不典型增生108例,两组差异有统计学意义(P<0.05);A组患者Hp感染307例,感染率为57.71%;B组患者Hp感染429例,感染率为72.84%,两组差异有统计学意义(P<0.05)。结论内镜下以萎缩性胃炎伴增生诊断率高于单纯萎缩性胃炎,且其合并肠上皮化生、不典型增生及Hp感染率较高,临床上更应该重视其诊断、治疗和随访。
OBJECTIVE To investigate the relationship between different appearance and pathology changes under gastroscope and Helicobacter pylori infections in the patients with chronic atrophic gastritis so as to guide the clinical diagnosis and treatment. METHODS A total of 8012 patients who underwent the endoscopy were enrolled in the study, the performance of endoscopic morphology, H. pylori infections and pathological results of patients diagnosed as chronic atrophic gastritis were analyzed ＂retrospectively. RESULTS Totally 1121 cases were diagnosed as chronic atrophic gastritis in 8012 cases. The group A included 532 patients（simple atrophic gastritis） ,the group B included 589 patients（atrophic gastritis with hyperplasia）. In the group A, 385 cases were diagnosed as the atrophic gastritis with the diagnosis accordance rate of 72. 37%. In group B, 505 cases were diagnosed as the astrophic gastritis with the diagnosis accordance rate of 85. 74%, the difference between the two groups was statistically significant（P〈0.05）. In group A,54 cases showed intestinal metaplasia, and 56 cases showed atypical hyperplasia. In group B, 94 cases showed intestinal metaplasia, and 108 cases showed atypical hyperplasia, the difference between the two groups was statistically significant （P〈0.05）. The Hp infections occurred in 307 cases of the group A with the infection rate of 57.71% and in 429 cases of the group B with the infection rate of 72.84%, the difference between the two groups was statistically significant （P〈 0. 05）. CONCLUSION The incidence of the intestinal metaplasia, dysplasia and Hp infections in the patients with chronic atrophic gastritis are higher than that in the patients with single chronic atrophic gastritis. More attention should be paid to the clinical diagnosis, treatment, and follow-up.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第10期2400-2402,共3页
Chinese Journal of Nosocomiology
关键词
萎缩性胃炎
胃镜
幽门螺杆菌
感染
Atrophic gastritis
Gastroscope
Helicobacter pylori
Infection
