摘要
目的:探索颅内静脉窦血栓形成(CVST)的病因、临床特征、影像学改变及诊治。方法:回顾分析11例CVST患者的临床资料,包括病因、临床表现、影像学异常表现等。结果:CVST的病因多样;临床表现无特异性;所有患者MRI和MRV可显示不同程度的静脉窦回流异常,DSA检查提示颅内静脉窦不同程度充盈缺损。结论:CVST临床无特异性,如临床有颅内高压征、局灶神经功能缺失、癫痫、低热等表现,病史追查发现有血液高凝状态、自身免疫性疾病及产褥期、妊娠、长期口服避孕药等因素,高度考虑此病的可能;MRI结合MRV检查可作为CVST早期诊断的首选方法。最好行DSA检查为金标准。如患者颅内压升高,有视力下降明显,要紧急处理颅内高压。所有CVT患者,维生素K拮抗剂治疗,INR目标值2.0～3.0。
Objective:explore the cerebral venous sinus thrombosis changes and the diagnosis and treatment of etiology,clinical characteristics,imaging.Methods:a retrospective analysis of the clinical data of 11 patients with CVST,including the abnormal performance of etiology,clinical manifestations,imaging.Results:the etiology of CVST diversity;the clinical manifestations were not specific;all patients with MRI and MRV showed abnormal venous reflux in different degree,DSA examination showed filling defect of different degree of intracranial venous sinus.Conclusion:CVST without specific clinical feature,such as the clinical manifestations of intracranial hypertension,focal neurological deficits,seizures,fever and so on,history tracing found hypercoagulability,autoimmune diseases,pregnancy and puerperium,oral contraceptives and other factors,highly consider this disease may be;MRI combined with MRV examination as the preferred method for early diagnosis of CVST.The best DSA examination as the gold standard.If the patients with elevated intracranial pressure,with decreased visual acuity,to emergency treatment of intracranial hypertension.All CVT patients,treatment with a vitamin K antagonist,INR target value of 2~3.
关键词
静脉窦血栓
诊断
治疗
venous sinus thrombosis
diagnosis
treatment
