摘要
目的:采用随机分类方法,观察两种方法治疗急性脑血管病并发应激性溃疡出血疗效。方法:将84例急性脑血管病患者随机分为两组,泮托拉唑组42例给予泮托拉唑40mg加入生理盐水或5%葡萄糖注射液100ml静滴,维持30~60分钟,1次/日,共10天;奥美拉唑组42例给予奥美拉唑40mg加入0.9%生理盐水或5%葡萄糖注射液100ml静脉点滴,维持30~60分钟,1次/日,共10天。结果:泮托拉唑组总有效率90.3%,奥美拉唑组总有效率66.5%,差异有显著性(P<0.05)。两组不良反应比较,差异没有显著性(P>0.05)。结论:泮托拉唑比奥美拉唑更能有效的治疗急性脑血管病并发应激性溃疡出血,安全可靠。
Objective : Use the method of Ran- dora assortment and observe curative effect of the two ways in treating cute cerebrovas- cular disease complicated with stress ulcer. Methods: Put 84 patients randomly divided into two groups. 42 cases of Pantoprazole group:add 0.9% of physiological saline or 100ml of 5% glucose injection,infusion so- lution, into 40rag of Pantoprazole. Last fi)r 30rain to 60min,quaque die for 10 days. 42 cases of Omeprazole group: add 0. 9% of physiological saline or 100ml of 5% glucose injection, ir^fusion solution, into 40rng of Omeprazole. l,ast for 30rain to 60rain, quaque die for 10 days. Result:The clinical efficacy rate of Pantoprazole is 90.3%. The clinical efficacy rate of Omeprazole is 66. 5%. The difference of the two groups was significant( P 〈 0.05 ). Comparing the ad- verse reaction of the two groups, the differ- ence of the two groups wasn' t significant( P 〉 0.05 ). Conclusion : Pantoprazole is more effective,safe and reliable than Omeprazole in treating acute cerebrovaseular disease complicated with stress ulcer bleeding