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2型糖尿病微血管病变的患病率及其临床危险因素分析 被引量:6

The prevalence and clinical risk factors of microangopathy in type 2 diabetes mellitus
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摘要 目的 :分析 2型DM患者微血管病变 (DMIP)的患病率及其临床危险因素。方法 :对 1993年 3月 1998年 7月在我科住院或门诊的 12 17例 2型DM进行回顾性调查。按有无糖尿病视网膜病变 (DRP)和糖尿病肾病 (DNP)分组 ,分别统计其患病率 ,用logistic多元回归分析微血管病变的相关因素和危险因素。 结果 :DRP的总患病率为 2 4 9% ,其中背景性视网膜病变和增殖性视网膜病变分别为 2 1 0 %和 3 9% ;DNP的总患病率为19 3% ,其中微量白蛋白尿 ,临床蛋白尿和肾功能不全分别为 10 0 % ,5 9%和 3 4%。Logistic回归结果显示 ,DM病程 (COUR)、平均动脉压 (MBP)、HbA1c、糖尿病神经病变 (DUP)和DRP是DNP的独立危险因素 ,COUR、MBP、HbA1c、TG、CH、DUP和DRP和DNP是独立危险因素。结论 :DRP和DNP的患病率分别为 2 4 9%和19 3%。COUR、MBP、HbA1c、DUP和DNP是DRP独立危险因素 ,DM病程 ,MBP、HbA1c、CH、TG。 Objective:To investigate the prevalence and clinical risk factors of DMIP in type 2 DM. Methods:Retrospect investigation was performed on 1 217 patients with type 2 DM who were hospitalized or in the out patient department in our hospital from 1993 to 1998. The patients were classified based on the present or absent of DRP or DNP. The prevalence of DRP and DNP were calculated. The risk factors of DMIP were determined. Results:The prevalence of DRP was 24 9%, among which the prevalence of BDP and PDR was 21 0% and 3 9% respectively. The prevalence of DNP was 19 6%, among which the prevalence of MAU, CPU and CRF was 10 0%, 5 9% and 3 4% respectively. The logistic analysis showed COUR, MBP, HbA1c, DUP and DNP were the risk factors for DRP; while COUR, MBP, HbA1c, TG, CH, DUP and DRP were the risk factors of DNP. Conclusion:The prevalence of DRP and DNP in our study was 24 9% and 19 3% respectively. The COUR, MBP, HbA1c, DUP and DNP were the risk factors for DRP; COUR, MBP, HbA1c, TG, CH, DUP and DRP were the risk factors of DNP.
出处 《军医进修学院学报》 CAS 2000年第3期211-214,共4页 Academic Journal of Pla Postgraduate Medical School
关键词 Ⅱ型糖尿病 微血管病变 危险因素 患病率 DMIP type 2 diabetes diabetic microangiopathy risk factors
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  • 1王晓东,中华内分泌代谢杂志,1996年,6卷,29页

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