摘要
目的探讨小剂量氯胺酮复合麻醉下子痫剖宫产患者血浆ＴＸＢ２、６－Ｋｅｔｏ－ＰＧＦ１α的变化及呼吸循环的影响。方法 采用放射免疫法测定１６例子痫患者和１６例非妊高征产妇剖宫产在氯胺酮麻醉下的血浆ＴＸＢ２、６－Ｋｅｔｏ－ＰＧＦ１α的变化并监测其呼吸循环的改变。结果麻醉后两组ＴＸＢ２变化不明显，而子痫组 ６－Ｋｅｔｏ－ＰＧＦ１α显著增大（Ｐ＜０．０５）；且病人安静，呼吸循环趋于稳定，临床效果显著。结论小剂量氯胺酮复合麻醉对子痫患者剖宫产是一种简便、安全有效的麻醉方法。
Objective To study the effect of ketamine combined anesthesia on plasma TXB2 and 6-Keto-PGF1α and on respiration and circulation in patients with puerperal eclampsia during ceasarean section. Methods Plasma TXB2 and 6-Keto--PGF1α were determined with radioimmunoassage (RIA)in both 16 patients with puerperal eclampsia and 16 without hypertension induced by pregnance before and during cesarean section. Meantime, the patients' respiration and circulation were monitored. Results The results showed the variance of plasma TXB2 was not significant in both groups during ketamine anesthesia. But plasma 6 --Keto --PGF1α increased significantly (P<0.05) under ketamine anesthesia in the patients with puerperal eclampsia. All the patients went smoothly through the period of operation without abnormality of respiration and circulation. Conclusion Ketamine anesthesia can be recommended as a simple, safe, and effictive way to be used in cesarean section of puerperal eclampsia.
出处
《江西医药》
CAS
2000年第4期199-200,共2页
Jiangxi Medical Journal
