摘要
目的总结阜外心血管病医院应用植入型心律转复除颤器（ICD）治疗致心律失常性右心室心肌病（ARVC）的经验。方法入选我院2004年3月至2012年3月确诊并植入ICD的ARVC患者，收集临床资料，进行常规电话及门诊随诊。结果共18例患者[男12例，女6例，平均年龄（46．4±13．8）岁]入选，平均随访（46．6±30．5）个月，有6例患者出现了111次室性心动过速（VT）／心室颤动（VF）事件，其中仅1次VF事件，其余均为VT事件，其中3例患者术后共出现了7次电风暴。ICD治疗组中的C反应蛋白（CRP）明显高于ICD未治疗组。111次VT／VF事件中，12次经电除颤终止心动过速，其余均通过抗心动过速起搏（ATP）终止了心动过速。结论ARVC患者ICD植入后的VT／VF事件以VT为主，多数可经ATP终止；出现电风暴的ARVC患者易反复发作恶性心律失常；CRP可能对ICD治疗具有预测价值。
Objective To evaluate the role of implantable cardioverter defibrillator（ICD） therapy in patients with arrhythmogenic right ventricular cardiomyopathy （ ARVC ）. Methods From Mar. 2004 to Mar. 2012 ,ARVC patients received ICD were enrolled in this study, and the clinical characteristics were collected. In the follow-up,we assessed the incidence, feature and ICD therapy in these patients. Results Eighteen patients were enrolled [ 12 men, 6 women, mean age （ 46. 4± 13.8 ） years 1. During the （ 46. 6± 30. 5 ） months followup period, ICD recorded 111 ventrictdar tachycardia （VT）/ventricular fibrillation （VF） episodes （ 1 VF, 110 VT） in 6 patients. Among these,3 patients experienced 7 electrical storms （ES）. Compare to patients without ICD therapy, C-reactive protein （CRP） level was higher in ICD therapy group. Among VT/VF episodes, 12 episodes were terminated by shocks ,99 episodes were terminated by anti-tachycardia pacing（ATP）. Conclusions VT episodes were very common in ARVC patients, most of them could terminated by ATP. Repeated episodes of malignant arrhythmias in ARVC patients with ES were common. CRP level might be a significant predictor of appropriate ICD therapy in ARVC patients.
出处
《中华心律失常学杂志》
2013年第2期127-129,共3页
Chinese Journal of Cardiac Arrhythmias
关键词
致心律失常性右心室心肌病
植入型心律转复除颤器
C反应蛋白
Arrhythmogenic right ventricular eardiomyopathy
Implantable eardioverter defibrillator
C- reactive protein
