摘要
目的观察初诊断2型糖尿病(type 2 diabetes mellitus,T2DM)患者糖尿病周围神经病变(diabetic pe-ripheral neuropathy,DPN)的患病率,并分析相关危险因素的影响。方法收集初诊断T2DM患者153例,分为DPN组和无糖尿病周围神经病变(NDPN)组。采集所有患者一般资料和相关生化指标。DPN的诊断标准采用2010年中国糖尿病防治指南的标准。结果 DPN在初诊断T2DM中患病率为38.56%;DPN组空腹血糖和糖化血红蛋白(HbA1c)高于NDPN组,空腹C肽低于NDPN组(均有P<0.05),其余指标两组间差异均无统计学意义(均有P>0.05);Logistic回归分析显示HbA1c是DPN的独立危险因素。结论研究结果提示临床医生在糖尿病早期即应该干预DPN和相关危险因素。
Objective To determine the prevalence of diabetic peripheral neuropathy （DPN） and risk factors as-sociated with DPN in newly diagnosed type 2 diabetic patients. Methods The last recruited 153 newly diagnosed T2DM patients including DPN group and non-DPN （NDPN） group were analyzed in this study. A standard epidemiological ques-tionnaire was used to collect life habits and personal history information. Blood pressure, height, weight, blood glucose, C-peptide, blood lipids and other biochemical index were measured. DPN was diagnosed using the China guideline for type 2 diabetes. Results The prevalence of neuropathy was 38. 56%. The levels of FBS and HbAle in the DPN group were sig- nificantly higher than those in the NDPN group. The level of fasting C peptide in the DPN group was significantly lower than that in the NDPN group. DPN was significantly associated with HbAlc by Logistic regression analysis. Conclusions The risk factors associated with DPN were HbAlc. More attention is needed to prevent DPN in newly diagnosed T2DM patients.
出处
《中华疾病控制杂志》
CAS
北大核心
2013年第5期374-376,共3页
Chinese Journal of Disease Control & Prevention
基金
安徽省高等学校省级自然科学基金(KJ2012Z177)
安徽医科大学校级科学基金(2012xkj057)
关键词
糖尿病
2型
患病率
危险因素
Diabetes meUitus, type 2
Prevalence
Risk factors
