摘要
【目的】探讨婴幼儿轮状病毒性肠炎与佝偻病的临床关系。【方法】检测轮状病毒性肠炎合并佝偻病（A组）和轮状病毒性肠炎患儿（B组）血清钙（Ca2＋）、磷（P怕）、骨碱性磷酸酶（BALP）以及免疫五项的含量，与健康体检儿童（C组）进行比较。【结果】①A组和B组Ca2＋、P＋2平均值均低于C组（均P〈0．05），且A组低于B组，而A、B两组的BALP均高于c组（P〈0．01）。②A、B两组中IgG、IgA、IgM正常例数和正常率均低于c组，而A组又明显低于B组（均P〈O．05）。③A、B两组小儿经过补液、抗病毒、合并佝偻病的同时补充维生素D等综合治疗，A组在治疗后IgG、IgA和IgM的正常例数和正常率均明显高于治疗前（P〈0．05）。④A、B两组治疗后，A组总有效率（75．00％）明显低于B组（95．00％）。【结论】佝偻病的患儿容易患轮状病毒性肠炎，可能与抵抗力下降有关。及时治疗佝偻病，不仅有助于婴幼儿轮状病毒性肠炎的尽早恢复，同时可提高患儿的机体免疫力。
[Objective] To explore clinical relationship between infant rotavirus enteritis and rickets. [Methods] Serum calcium（Ca2＋ ）, phosphorus （P ＋ 3 ）, bone alkaline phosphatase （BALP） as well as the im- mune five indicators in infant rotavirus enteritis complicated with rickets（group A） and infant rotavirus enteri- tis（group B）. The above indicators in group A and group B were compared with healthy children（group C）. [Results]The mean level of Ca2＋ and p＋3 in group A and group B was lower than that in group C（all P G 0.05）, while that in group A was lower than that in group ]3, but BALP in group A and group B was higher than that in group C（ P d0.01）. The number of patients with normal IgG, IgA and IgM and the normal rate in group A and group B were lower than those in group C, but those in group A were obviously lower than those in group B（all P G0.05）. After the comprehensive treatment such as fluid infusion, anti-virus and sup- plement of vitamin D, the number of patients with normal IgG, IgA and IgM and the normal rate in group A were obviously higher than those before treatment（ P G0.05）. After the treatment, the total effective rate in group A（75.00%） was obviously lower than that in group B（95.00%）. [Conclusion]Children with rickets are susceptible to rotavirus enteritis, which may be associated with the decreasing of resistance. Prompt treatment Of rickets can not only be helpful for the early recovery, but also increase the immunity of children.
出处
《医学临床研究》
CAS
2013年第4期707-709,共3页
Journal of Clinical Research
