摘要
目的 探讨激光吻合颅神经的可能性 .方法 家猫10只的两侧动眼神经在颅内段切断 ,分别以 CO2 (12 0 m W,光斑长 0 .2 cm,宽 0 .3mm)激光原位吻合或常规纤维蛋白粘合剂修复 ,术后进行瞳孔对光反射、神经纤维直径、通过率等指标的观察 .结果 14wk后激光吻合组瞳孔对光反射功能优于纤维蛋白粘合剂组 ,激光组瞳孔直径为 2 .3mm,纤维蛋白粘合剂组为 3.1m m.神经组织学观察激光组轴突再生情况好 ,神经纤维通过率达 82 .0 % ,明显好于纤维蛋白粘合剂吻合组 71.0 % .结论 CO2
AIM To study the feasibility of carbon dioxide laser on severed cranial nerves. METHODS The bilateral intracranial oculomotor nerve of cats were transected. Then one side was welded by linear mode carbon dioxide laser at the local site, and another side repaired by fibrinogen tissue adhesive. Reflextion of pupils, diameter of regenerationfibers and rate of fibers crossing anastomosis area were recorded and analysed postoperatively. RESULTS After 14 weeks, the pupil of the laser anastomosis side recovered from amplifying in denervation; the pupil diameter was 2.3 mm, the fibrinogen tissue adhesive sides was 3.1 mm. Histomorphological examinations revealed good axon regeneration. The rate of nerve fibers crossing laser anastomosis area was 82.0%; the fibrinogen tissue adhesive sides was 71.0%, and no remarkble damages were found. All these were superior to the fibinogen tissue adhesive group. CONCLUSION The carbon dioxide laser can be used effectively in the microsurgical repair of cranial nerves.
出处
《第四军医大学学报》
2000年第9期1147-1149,共3页
Journal of the Fourth Military Medical University
关键词
颅神经
纤维蛋白粘合剂
修复
CO2激光
laser
fibrinogen tissue adhesive
nerve repair
nerve anastomosis
oculomotor nerve
