摘要
目的：对检测幽门螺杆菌粪便抗原诊断幽门螺杆菌（Ｈｐ）感染的准确性进行临床评价。方法：采用酶联免疫分析法检测９４例因上消化道症状接受胃镜检查病人的幽门螺杆菌粪便抗原（ＨｐＳＡ），以快速尿素酶、组织学检测结果作为诊断Ｈｐ的标准。结果：在快速尿素酶、组织学检查均阳性的４４例中，ＨｐＳＡ检测为阳性的有 ４２例，阴性的有 ２例；而在快速尿素酶、组织学检查阴性的 ５０例中， ＨｐＳＡ检测为阴性的有４９例，阳性的有１例。 ＨｐＳＡ检测诊断 Ｈｐ感染的敏感性、特异性及准确性分别为 ９５％（４２／４４）、 ９８％（４９／５０）和 ９７％（９１／９４）。结论：ＨｐＳＡ检测是一种简便、准确的非侵入性诊断 Ｈｐ感染的方法，值得临床推广使用。
Objective: To evaluate the usefulness of helicobacter pylori (H pylori) stool antigen (HpSA) test as a predictor of H.phylori status. Methods: Stool specimens of 94 patients who had gastroscopy with biopsy at our endoscopy unit were collected.H py- loristatus was defined positive (or negative)if both histology and rapid urease test were positive (or negative). A specific enzyme-linked immunosorbent assay (ELISA)was used tO test the stools for the presence of H pylori antigen. Results: Forty-four patients were diag- nosed as H phlori positive and fifty as negative by histology and rapid urease test. The HpsA test was positive in 42 of M patients and negative in 49 of 50 patients. Sensitivity, specifity and diagnostic accuracy of HpSA were 95%(42/44), 98%(49/50)and 97%(91/94) respectively. Conclusion: HpSA is a noninvasive, simple, relible method for evaluating H.pylori status.
出处
《新医学》
2000年第10期587-588,共2页
Journal of New Medicine
关键词
幽门螺杆菌粪便抗原
幽门螺杆菌感染
诊断
胃镜
Helicobacter pylori antigen Helicobacter pylori Infection Diagnosis Gastroscop(
