摘要
目的:探讨心理治疗联合氟西汀对前列腺癌患者围手术期焦虑、抑郁症状的治疗效果。方法:本研究对2010年3月至2012年10月住院期间的127例前列腺癌患者采用汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)和汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)进行焦虑、抑郁症状评分。并与127例非肿瘤疾病的男性泌尿系疾病患者对照。将伴焦虑或(和)抑郁症状的83例患者随机分为对照组、心理治疗组、氟西汀治疗组以及心理治疗联合氟西汀治疗组,以汉密尔顿焦虑量表和汉密尔顿抑郁量表的评分作为治疗效果的评价标准。结果:前列腺癌患者伴发焦虑、抑郁症状的发生率明显高于非实体肿瘤的患者(P<0.05),患者经心理治疗或氟西汀治疗后汉密尔顿焦虑量表和汉密尔顿抑郁量表的评分较对照组显著下降(P<0.05),心理治疗较氟西汀治疗疗效更为显著(P<0.05),心理治疗联合氟西汀治疗较单独采用氟西汀或心理治疗的HAMA、HAMD评分下降更为显著(P<0.05)。结论:心理治疗联合氟西汀治疗前列腺癌围手术期患者的焦虑、抑郁症状疗效满意,且明显提高了患者的生活质量。
Objective:To investigate the efficacy of psychotherapy combined with fluoxetine on prostate cancer patients with anxiety and depression during the perioperative period.Methods: 127 hospitalized patients with prostate cancer were investigated by using Hamilton Anxiety Scale(HAMA) and Hamilton Depression Scale(HAMD) from March 2010 to October 2012,then compared with 127 patients with non-prostate canccer.83 patients' HAMD scale over 20 and HAMA scale over 14,were randomly divided into control group,psychotherapy group,fluoxetine group and the combination group.Results: The rate of depression and anxiety in prostate cancer patients were higher than non-tumor patients(P<0.05);After the treatment,the scores of HAMD and HAMA in psychotherapy group and fluoxetine group were less than that of before(P<0.05),and the treated efficacy of psychotherapy was better than that of fluoxetine(P<0.05).The scores in the combination group was significantly less than in psychotherapy group and in fluoxetine group(P<0.05).Conclusion: The compound therapy of psychotherapy with fluoxetine can obviously improve the state of anxiety and depression in prostate cancer patients during the perioperative period,and enhance the quality of the patients' life.
出处
《山西职工医学院学报》
CAS
2013年第2期21-24,共4页
Journal of Shanxi Medical College for Continuing Education
关键词
心理治疗
氟西汀
前列腺癌
围手术期
焦虑
抑郁
posychotherapy
fluoxetine
prostate cancer
perioperative period
anxiety
depression
