摘要
目的:了解我院2010年12月至2012年8月份发生的药品不良反应(ADR)的一般情况及相关因素,为临床合理用药提供参考。方法:对我院2010年12月至2012年8月份发生的104例不良反应进行分析、归纳、总结。结果:ADR涉及的药品中抗感染药物居首位,占78.85%;静脉滴注给药途径比例最大,占70.19%;累及器官/系统方面以皮肤及附件损害最为常见,占62.16%。结论:抗感染药物应用及静脉滴注用药是产生ADR的主要因素。临床应加强ADR高发生率品种的监管,注意选择合适的用药方式,强化ADR的监测报告,保证药物使用的安全、有效、促进临床合理用药。
Objective： To learn the situation and the related factors of ADRs occurred in our hospital and to provide reference for rational drug use. Methods： 104 ADR reports were collected in our hospital from December 2010 to August 2012 and the data were analyzed, and summarized retrospectively. Results： Anti-infective drugs were the most commonly used drugs and were 78.85%. 70.19% of ADRs were induced by intravenous drip infusion; the most common clinical manifestations were the damage of skin and adnexa, which accounted for 62.16%. Conclusion： The use of anti-infective drugs and the intravenous drip infusion are the main factors of infecting easily. Supervision of the varieties of high incidence of ADRs should be strengthened, attention should be paid to the way of using drugs and enhanced the reports of the ADR monitoring, to guarantee the safety, efficiency, and improve the rational use of drugs.
出处
《药品评价》
CAS
2013年第4期32-35,共4页
Drug Evaluation
关键词
药品不良反应
不良反应报告
合理用药
Adverse Drug Reaction
Adverse Reaction Reports
Rational Use of Drugs
