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传统心肌酶谱检测在诊断急性心肌梗塞(AMI)的临床意义 被引量:11

Detection of Traditional Myocardial Enzymes Clinical Significance in the Diagnosis of Acute Myocardial Infarction (AMI)
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摘要 目的:探讨传统心肌酶谱四项(CK、CK-MB、LDH、AST)检测在诊断急性心肌梗塞(AMI)的临床意义。方法:选择入住我院接受治疗的80例经临床诊断为急性心肌梗塞(AMI)患者作为观察组,并将同期于我院进行健康体检的80例作为对照组,于清晨空腹抽取静脉血,经离心分离出两组血清,并运用全自动生化分析仪对两组CK、CK-MB、LDH、AST进行测定,对比两组检测结果以及AMI患者相关性分析。结果:(1)观察组患者CK、CK-MB、LDH以及AST(单位:U/L)的浓度值分别为(766.7±55.4)、(73.1±17.2)、(332.3±112.2)、(152.5±77.6);正常对照组上述四个指标分别为(92.1±15.5)、(11.9±5.3)、(155.7±33.2)、(28.1±6.6)。两组均各指标均存在统计学差异(P<0.05)。(2)CK、CK-MB、LDH、AST升高程度与AMI范围呈显著的正相关性(P<0.01)。结论:传统心肌酶谱检测能够较准确地诊断AMI,具有十分重要的临床意义与价值。 Objective: To investigate the the traditional myocardial enzymogram four (CK, CK-MB, LDH, AST) clinical significance of detection in the diagnosis of acute myocardial infarction (AMI). Methods:80 cases of clinically diagnosed patients with acute myocardial infarction (AMI) were as observation group, and the other 80 cases of undergoing a physical examination in our hospital during the same time were as the control group. Fasting venous blood, centrifugation in serum, and the use of automatic biochemical analyzer were measured for two sets of CK, CK-MB, LDH, AST, compared two sets of test results and analysis of the patients with AMI. Results:(1) The observation of patients with CK, CK-MB, LDH and AST (units:U/L) concentration values were (766.7±55.4) (73.1±17.2) (332.3±112.2) (152.5±77.6);the four indicators of the normal control group were respectively (92.1± 15.5) (11.9 ±5.3) (155.7±33.2) (28.1±6.6). Both groups of each indicator had a statistically significant difference (P〈0.05). (2) CK, CK-MB, LDH, AST increased degree of AMI range showed a significant positive correlation (P〈0.01). Conclusion:Traditional myocardial enzymes detection could be more accurate diagnosis of AMI, had important clinical significance and value.
出处 《中国医药导刊》 2013年第4期713-714,共2页 Chinese Journal of Medicinal Guide
关键词 心肌酶谱 急性心肌梗塞(AMI) CK CK-MB LDH AST Myocardial enzymes Acute myocardial infarction (AMI) CK CK-MB LDH AST
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